CSIR FAQs CSIR provides Junior Research Fellowship in
various fields of Science & Technology and Medical Sciences. If you are a
bright postgraduate with an intense desire to do good science, the EMR Division,
HRD Group, CSIR would be delighted to hear from you.
Keep your eyes open for all-India press
advertisements that are published twice a year inviting applications. Just fill
in the prescribed application form and send the completed application form to
the Controller of Examinations, Examination Unit, CSIR Complex Building, Opp.
Institute of Hotel Management, Pusa, New Delhi –110 012. Also visit HRDG for
details.
The Selection for award of JRF is made on the
basis of a competitive written test called the National Eligibility Test (NET),
conducted by CSIR at national level and consisting of two papers. Paper – 1 is
objective type consisting of Part (A) general nature and part (B) is subject
type. It tests the mental ability and broad awareness of scientific knowledge.
You may choose the second paper from amongst (1) Chemical Sciences (2) Earth,
Atmosphere, Ocean and Planetary Sciences (3) Life Sciences, (4) Mathematical
Sciences and (5) Physical Sciences. For the second paper you will need to give
short descriptive answers.
Usually
examinations are held for a day on the third Sunday in June and December, each
year.
For more details visit:
Don’t worry, all candidates who qualify in the test will be informed individually after the results are finalised. Results are also posted on the Internet. Visit:HRDG
Junior
Research Fellowships are awarded each year by CSIR to those holding MSc or
equivalent degree, with minimum 55% marks after qualifying the National
Eligibility Test. Please visit HRDG
for details.
The minimum requirement is a First Class M.Sc./B. Tech. And you must
not be over 35 years. All reservations that are in force for all entitled
categories as per Government of India rules apply.
The basic salary for Scientist B or Group IV(1) is Rs. 8000-275-13500.
And a senior Scientist i.e., Scientist G or Group IV (6) would be in
the basic pay scale of Rs. 18400-500-22400.
You would be amazed to know about the many items of daily use that CSIR
has helped develop. Its contribution extends to almost all fields of human
activity, be it agriculture, health, defence, aero- dynamics, genetic
engineering and the development of India's first super computer. Eleven of the
14 new drugs developed in independent India are from CSIR.
The entire list would be too long so here is merely a sample. Amul baby
food, Nutan stove, Saheli a nonsteroidal once-a-week oral contraceptive pill for
women, E-mal for resistant malaria, Asmon, a herbal therapeutic for asthma,
SARAS, a multi-role aircraft, Flosolver India's first parallel computer; Swaraj
and Sonalika tractors, and the indelible ink that is the mark of a proud
Indian voter, are gifts of CSIR to the nation.
No wonder CSIR is recognized as one of the world's largest knowledge
enterprises
The “second battle of Haldighati,” is what the media dubbed a
pioneering case in a "rule-based" war in the context of what India
felt was a wrongly granted US patent on the use of turmeric for
wound healing.
The rule is that the applicant has a right to patent innovations only
after demonstrating the novelty, non-obviousness and usefulness of an article.
The use of turmeric for wound healing is not novel because it is a part of
India’s prior knowledge as recorded in ancient Sanskrit and Pali texts and
formal papers in journals such as The Indian Journal of Medical Research,
etc.
CSIR followed the recognized legal procedures and proved to the US
Patent Office that such use of turmeric in wound healing was clearly the
consequence of prior knowledge. The US Patent Office scrapped the patent. India
won that particular battle.
The CSIR Programme on Bioactives is a mammoth network programme being
coordinated by the R&D Planning Division (RDPD), CSIR. It engages 20 CSIR
laboratories, 13 universities and three well-known organizations in the
traditional system of medicine. It involves screening of Ayurvedic formulations,
plants, fungi, microbes and insects against 14 disease areas including cancer,
tuberculosis, filaria, malaria, ulcer, Parkinson’s and Alzheimer diseases, to
identify new lead molecules.
Work is being pursued in a well-coordinated manner with different
dedicated groups carrying out well-defined tasks. For example, The Indian Institute of Integrative Medicine (previously known as RRL, Jammu) is the
Nodal laboratory for investigation of all the Unani drugs. Its activities are to
participate in and coordinate plant collection, authentication, and finger printing. It
also participates in and coordinates the biological activities such as profiling
of the extract to evaluate anticancer activity (in vitro cytotoxicity),
and immunomodulatory and hepatoprotective (both in vivo and in vitro)
activities of the samples prepared by the participating institutes.
Certainly! The Herbal Therapeutics programme of CSIR involves efforts
to develop herbal preparations as therapeutics. These herbal preparations are
being developed only after conducting all the appropriate studies, viz.
standardization, biological activity validation, safety, efficacy and clinical
studies. Products developed would
be then introduced as therapeutics in the Indian and the foreign markets.
The CSIR collaboration with the AVS and CCRUM is a major initiative in
this direction.
As a leading S&T organization of a nation rich in marine bounty,
CSIR is also investigating our oceans. An all India coordinated project ‘Drugs
from the Sea’ funded by Department of Ocean Development, Government of India,
and coordinated by the Central Drug Research Institute, Lucknow, is being conducted in
collaboration with 10 participating laboratories for exploiting marine flora and
fauna for development of drugs as well as herbal remedies.
The programme covers all aspects of drug research including isolation of
active molecules, their characterization and development.
Several promising samples have been found.
Asthma
A mission mode programme on asthma has been launched for finding a cure
for this disease following the realization of CSIR’s role as a nodal player in
the field due to the existing expertise in its allergy group and promise shown
by its herbal medicine (Asmon) developed by the Indian Institute of Chemical
Biology, Kolkata. Studies carried
out by CSIR have already led to significant increase in the understanding of the
disease viz., atopic nature of asthma, identification, purification and
characterization of allergic proteins, identification of T-cell epitopes of
allergens, development of in vitro screening procedure using human
endothelial cell adhesion molecules, identification of the human lung surfactant
proteins in respiratory disorders, identification of SNPs in few candidate genes
for asthma, development and a mouse model of asthma.
The future studies envisaged include an integrated, networked and
focused mission aiming at (i) development of therapeutic modalities using SPD
and SPA; reversal of TH2 and TH1, response identification
of lead molecules by in vitro and in vivo model, (ii) a broad sample collection
of affected population, validation of genes involved, studies on gene
polymorphism, identification of molecular markers, interactions expressive genes
with other genes, determination of the genetic basis of asthma.
Psoriasis
Psoriasis is one of the most common dermatological
diseases affecting around 2 per cent of the world population but its cause and
pathogenesis are not clearly understood. Most importantly no preventive/curative
therapy exists for psoriasis except the symptomatic management.
Based on the traditional knowledge, the development of a
single plant based oral herbal formulation was initiated under NMITLI for making
it globally acceptable. The project
is being led by Lupin Laboratories as the industry partner.
Extensive studies comprising fingerprinting,
activity guided fractionation, efficacy studies, toxicology, safety
pharmacology, pharmaco-kinetics and toxico-kinetics enabled the filing of an
Investigational New Drug (IND) application for
the first time in the country. The
estimated market for psoriasis therapeutics is around 4 billion and the
development will enable India to capture a significant part of the market.
Latent
Tuberculosis
Worldwide, around two billion people are infected with M.
tuberculosis. Nearly, 8 million
new cases are added annually and the biggest burden is in South East Asia.
Around 3 million deaths owing to tuberculosis (TB) are reported every year and
India accounts for a substantial percentage. With the rampant Human
Immunodeficiency Virus (HIV), TB is reaching almost epidemic proportions. It kills
one in three people co-infected with HIV/AIDS. Furthermore, TB is a major
barrier to economic development, costing India over Rs. 12,000 crore a year.
Considering these aspects CSIR through the NMITLI scheme supported a project
entitled “Latent M. tuberculosis:
New targets, drug delivery systems and Bio-enhancers and therapeutics”
in the year 2001. Significant success has been achieved in the project.
An IND for a new pharmacophore for the treatment of
tuberculosis has been filed. This
is the first success achieved in developing a new tuberculosis therapeutic in
the last 40 years globally. The
molecule, Sudoterb, works through combination therapy (compatible with the
present drugs), is less toxic, clears the total infection within two months and
no recurrence has been observed. It fits well into the present four-drug therapy
by replacing one or two drugs from the present cocktail.
Some new drug targets have also been developed along with a novel drug
delivery system.
BioSuite
Eighteen research institutes and three industries, were
brought together to develop the comprehensive, portable and versatile software
package christened ‘BioSuite’. Led by TCS, the team has developed the
software, which will serve as a multipurpose tool for carrying out diverse
bioanalyses ranging from gene analysis to comparative genomics, pathway modeling
to homology modeling and molecular visualization & manipulation to drug
designing. The software has several
unique features, which are not present in similar other packages available in
the market. BioSuite comprises
eight modules involving 114 sub modules and 243 algorithms.
SofComp
The NMITLI project entitled, "Cost effective Simple
Office Computing (SofComp) platform to replace PC" sought to develop
platform technology based on Linux. The
Simple Office Computers (SofComp) are thus based on a System-on-Chip
architecture with a high degree of integration and several innovative features.
The Auto Fuel Policy drafted under the Chairmanship of
Dr R. A. Mashelkar, has paved the way for laying Indian standards for auto
emissions and thus moving towards meeting the global settings in the domain.
The standards ‘Bharat II, III & IV’ will come into force in
phases as per the road map evolved. Improvement in fuel quality is the prime
need in addition to changes required in auto engines, use of catalytic
converters, etc.
Under a NMITLI supported programme, effort has been
initiated to help improve fuel quality and a novel catalyst has been developed.
The catalyst has remarkable efficiency for desulfurizing diesel, obtained
from the first stage of an HDS unit with sulphur (S) content of about 2500 ppm
to less than 50 ppm. It performs at the typical refinery process conditions,
i.e., < 340º C and 40-bar pressure. The catalyst developed is even active at
30-bar pressure. The development
would be of immense help in providing quality diesel as per Bharat III to IV
emission standards. Efforts are on
to identify a refinery to test the catalyst in plant environment.
The Traditional
Knowledge Digital Library (TKDL) is a collaborative project with the
Department of AYUSH, Ministry of Health and Family Welfare, Government of India. The main objective of this network project is to prevent
misappropriation of India’s rich heritage of traditional knowledge.
India has had unsavoury experience of noting the grant of wrong patents
on turmeric by USPTO and neem by EPO. These
patents were successfully challenged by India and revoked in an expensive and
time-consuming process.
The TKDL database provides an easily accessible and
retrievable source for patent examiners to verify claims relating to traditional
knowledge. The First phase of TKDL-Ayurveda presents information and images
gleaned from 14 Ayurvedic texts and transcribed in five international languages
-- English, German, French, Spanish and Japanese, using an innovative IT
software. Over 36,000 formulations have been transcribed in patent application
format. Currently work is in progress on the second phase, which will cover
Unani, Siddha, and the residual work on Ayurveda. TKDL-Unani will cover 77,000
formulations.
TKDL has been able to set international specifications
and standards for setting up of TK databases and registries based on TKDL
specifications. This was presented at the fourth session of Intergovernmental
Committee (IGC) of WIPO on Intellectual Property and Genetic Resources,
Traditional Knowledge and Expression of Folklore. The Technical Standards
presented by India were adopted by the Committee in the fifth session of the IGC.
TKDL has been heralded as a model for other countries
for protecting their Traditional Knowledge from misappropriation, and many
countries are seeking collaboration with CSIR in this area.
Saras is a 14-seater twin-engined turboprop aircraft fully
pressurized for passenger comfort. It has a maximum speed of over 600 km/h and a
maximum range of 1200 km. Its state-of-the-art avionics, electrical,
environmental control and other systems make it a contemporary aircraft of the
21st century
The
CSIR efforts at Tsunami relief have been timely, multi-faceted and large. A
number of CSIR laboratories rose above the occasion to offer their scientific
and technical skills and resources to mitigate the sufferings of the survivors.
The offers and initiatives include shelter, food, drinking water, and ongoing
studies that in future would improve our knowledge and skills to deal with such
disasters.
CFTRI,
Mysore, took upon itself the mission of providing food to the survivors. It
undertook the largest production of instant food in its history. More than two
tonnes of food was sent daily to the affected areas for about seven days to
cater to about 50,000 to one lakh meals. Food items even took into account
culinary preferences of the local people and the special nutritional
requirements of children.
CSMCRI,
Bhavnagar, provided drinking water supply in the affected areas by reverse
osmosis process.
CBRI,
Roorkee, rushed a team of scientists to the affected areas.
It is poised to provide backup support in rehabilitating devastated areas
by providing pragmatic solutions to the repair and retrofit of existing
infrastructure.
SERC, Chennai,
has proposed to help the survivors in structural assessment of damaged buildings
and would suggest repairs/remedial measures.
NIO
scientists are working on a system to detect earthquakes below the ocean floor.
NGRI’s
Seismological Observatory recorded the earthquake and its after-shocks. It
continues to monitor the area and provides information so that appropriate
action may be taken and loss to life and property minimised.