| Professional Appointments |
Positions Held |
Period |
Name of Organization |
Secretary, DSIR & Director General, CSIR |
November 2007- Present |
Secretary, Department of Scientific and Industrial Research, Govt. of India. & Director General, Council of Scientific and Industrial Research |
Director |
11th August 1997-November 2007 |
Institute of Genomics & Integrative Biology (CSIR), Delhi |
Professor |
June 1997 - August 2001 |
Molecular Biophysics Unit, Indian Institute of Science, Bangalore |
Associate Professor |
April 1992-June1997 |
Molecular Biophysics Unit, Indian Institute of Science, Bangalore |
Visiting Professor |
May-July 1997 |
Max. Planck Institute of Biophysical Chemistry, Goettingen, Germany |
Associated Faculty |
April 1989-March 1995 |
Centre for Genetic Engineering, Indian Institute of Science, Bangalore. |
Asst. Professor |
April 1986 - March 1992 |
Molecular Biophysics Unit, Indian Institute of Science, Bangalore |
Lecturer |
April 1981 - March 1986 |
Molecular Biophysics Unit, Indian Institute of Science, Bangalore |
Research Associate |
December 1979-March 1981 |
Molecular Biophysics Unit, Indian Institute of Science, Bangalore |
Visiting Scientist |
November 1979 |
Dept of Biochemistry, Memorial University of Newfoundland, St. Jones, Newfoundland, Canada |
Post-Doctoral |
September 1978-October 1979 |
French Govt. fellowship Institute, de Rechercheen Biologie Moleculaire CNRS, Univ. of Paris, Paris VII |
Adjunct Professor |
June 2003-Present |
Bioinformatics Centre University of Pune, Pune |
Visiting Professor |
January 1998-Present |
B. R. Ambedkar Centre for Biomedical Research, University of Delhi, Delhi |
Awards and Honours |
|
Name of Award |
Conferring Agency |
Year |
|
National Science Talent Search Scholarship |
NCERT, INDIA) |
1968 |
|
Young scientist medal |
Indian National Science Academy |
1979 |
|
Kani medal |
National Cancer Research Centre,Tokyo, Japan |
1981 |
|
Cama Memorial Award |
Society of Biological Chemists, India |
1990 |
|
Shanti Swarup Bhatnagar Award in Biological Sciences |
Council of Scientific & Industrial Research, India |
1990 |
|
C. R. Krishnamurthy Oration Award |
Society of Biological Chemists (India) |
1998 |
|
FICCI Award 1998-99 in recognition of individual initiative in Life Sciences including agriculture |
Federation of Indian Chambers of Commerce and Industry |
1999 |
|
Millennium Medal |
Indian Science Congress |
2000 |
|
Ranbaxy Research Award for The Year 2001 in the field of “Medical Sciences – Medical
Research” |
Ranbaxy Science Foundation |
2002 |
|
Goyal Prize 2001 in the field of Life Sciences. |
Kurukshetra University |
2003 |
|
B. K. Bachhawat Oration Lecture Award |
JNU |
2003 |
|
C. R. Krishnamurthy Oration Award |
CDRI |
2003 |
|
Prof. P.K. Bose Memorial Award |
Indian Chemical Society |
2004 |
|
Dr. B.R. Ambedkar Centenary Award for excellence in biomedical research |
Indian Council of Medical Research |
2005 |
|
H. K. Firodia Awards For Excellence In Science and Technology |
H.K. Firodia Memorial Foundation |
2007 |
|
Dhirubhai Ambani Oration Award |
|
2007 |
|
Padma Bhushan Dr. RA Mashelkar Medal |
Asian Paints |
2007 |
|
Chemcon Distinguished Speaker Award |
|
2007 |
|
2005 VASVIK Award for Biological S&T |
Vividhlaxi Audyogik Samshodhan Vikas Kendra |
2008 |
|
Prof. M.V. Pylee Lifetime Achievement Award |
|
2008 |
|
6th Biospectrum person of the year-2008 |
Biospectrum |
2008 |
|
Distinguished Alumni IISc |
IISc Alumni Association |
2008 |
|
SS Bhatnagar Memorial Award and Gold Medal |
Indian Science Congress |
2009 |
|
The Jagadis Chandra Bose Medal (2007) |
INSA |
2009 |
|
2008 Shri Om Prakash Bhasin Award for S&T (Biotechnology) |
Shri O. P. B.Foundation for S&T |
2009 |
|
D.Sc. Degree (honoris causa) |
Vidyasagar University |
2009
|
Membership/Fellowships to Academies and Scientific Bodies |
|
Elected member |
Guha Research Conference (India) |
1986 |
|
Fellowship of the Indian Academy of Sciences |
Indian Academy of Sciences |
1991 |
|
Elected member |
Human Genome Organization (HUGO) |
1991 |
|
Fellowship of the Indian National Science Academy |
Indian National Science Academy |
1995 |
|
Elected Council Member Biochemistry and Molecular Biology |
Federation of Asian & Oceanic |
1995 |
|
Fellowship of the National Academy of Sciences, Allahabad |
National Academy of Sciences |
2000 |
|
Elected Council Member, HUGO |
Human Genome Organisation (HUGO) |
2004 |
|
Fellow of Biotech Research Society of India (BRSI) |
Biotech Research Society of India (BRSI), RRL, Trivandrum |
2005 |
|
Fellow of Indian National Academy of Engineering |
Indian National Academy of Engineering, New Delhi |
|
2009 |
- Major Scientific Achievements
Prof. Brahmachari has demonstrated the structural flexibility of DNA and the role of repetitive sequences in DNA transactions much before the discovery of repeats association with genetic disorders. His work on the structural flexibility of telomeric repeat sequences is one of his well cited contributions. He has made major contributions in molecular analysis of genetic disorders associated with trinucleotide amplification and repetitive sequence instability. Using a combination of structural biology, computational genomics and population based polymorphism scanning he and his group have provided a novel structural frame work for understanding the etiology of several neurological disorders. He was first to establish a close clinical network to address genetics of complex disordres and demonstrated association of two genes to Schizophrenia and Bipolar Disorder (synaptogyrin 1 and MLC1 gene) and identified several SNPs and other markers associated to various neurological disorders. Taking advantage of genetic diversity of Indian population and core expertise in structural biology and computation, he has pioneered functional genomics initiative in India and and led the Indian Genome Variation Consortium which developed a database of over 1000 genes related to disease and drug response, exploring human genome variation in multi-ethnic, multi-lingual populations of India to develop a national resource: the genetic profile of the people of India.
Prof. Brahmachari and coworkers have carried out extensive computational analysis of the repetitive sequences in the genome and were one of the first to propose functional role of such sequence. He and his associates have developed novel and unique tools for genome annotation and identification of functional signature for hypothetical proteins in the genome through comparative genomics approach. He and his group has developed novel software for genome analysis and identified several novel non-active site targets for bacterial pathogen under a national network project in In Silico Biology for drug target development led by him. He is also the first to market novel globally competitive Bioinformatics software products from CSIR. His group has also developed tools for System Biology Platform. Recent finding of Prof. Brahmachari and his associates that Human miRNA can target critical genes in HIV, thus preventing HIV proliferation has received wide international recognition. (Petit-Zeeman, S. Nature Rev. Drug Discovery, 2006, 5.5). His group has developed computational model for gene-gene interaction network for complex disorders like Schizophrenia.
Prof. Brahmachari has also been involved in issues relating to Human Genome research ethics and Human Rights. As a member of the steering committee of the International Human Rights Commission he has contributed to the formulation of the draft guidelines in terms of benefit sharing by the populations that are the part of the research endeavor as resources of genetic material and addressed issues of unethical exploitation of genetic resources of the Third world. His contribution in India in promoting genomics research through thrust area development in granting agencies, lectures, courses and human-resource training is very significant. Dr. Brahmachari has contributed significantly in promoting industry-academia interactions through novel program of knowledge partnerships in genomics and bioinformatics.
Prof. Brahmachari has positioned IGIB as Institution of Knowledge generation and Development and established alliances with industries who are expert in production, marketing and wealth generation. GENOMED Alliance and TCGA project are outcomes of such strategy.
Prof. Brahmachari was first to conceptualize and implement Genomed, a first-of-its-kind alliance in India between a government Institute and a pharmaceutical company - Nicholas Piramal India Limited & a CSIR lab - Centre for Biochemical Technology (CBT) now IGIB. This knowledge alliance was dedicated to the study and advancement of genomics, pharmacogenomics and bioinformatics. This model allowed knowledge generation and absorption by industry simultaneously and this was distinctly different from contractual research or technology transfer. The first predictive diagnostic medicine for drug nonresponders of Asthma has been developed. The project has so far filed 2 international patents.
Prof. Brahmachari has also conceptualized creation of TCGA, “The Centre for Genomic Application”. It is a collaborative R&D project between The Chatterjee Group and IGIB/CSIR/DST that is used as a shared resource for all the research centres in the country; be it public or private. TCGA is a trendsetter in this direction, where a world class high throughput facility/infrastructure required to harness the knowledge coming out Human Genome research is established jointly by industry and the Institute.
In summary, Prof. Brahmachari has shown exemplary scientific leadership and has made contribution in the area of Functional Genomics with special emphasis on molecular genetics of neurological and psychiatric disorders and functional Genomics in silico. Prof. Brahmachari’s scientific contribution has positioned India on the world genome research map (Nature, Vol. 436; pp 480-483 and pp 492-495; 28th July, 2005).
- Involved in courses in Bio-molecular Structure; Biophysical Chemistry, DNA Structure-Function and Expression for a large number of Ph.D. students at Indian Institute of Science for 18 years.
- Delivered over 200 lectures at various institutions, universities and colleges in the country on Human Genome Project and Genome Analysis Technology.
- Has delivered lectures for the Integrated Ph.D students of B. R. Ambedkar Centre for Biomedical Research, University of Delhi, Delhi from 1998 onwards.
- Dr. Brahmachari’s contribution in Institutional Transformation
Relatively unknown Centre for Biochemical Technology of CSIR underwent major transformation over the last 10 years to emerge as a leading institute of Genomics & Integrative Biology in the country. The scientific production and quality grew from 7 publication (Avg. IF 1.01) in 1996 to 75 (Avg. IF 3.30) in 2006 and expected to reach higher in 2007. It also acquired an impressive portfolio of 67 foreign and national patents (and 176 pending patents). IGIB’s patent portfolio has caused value realization and IP asset creations and has attracted foreign and national collaborations and project funding. The following are the salient achievements of CBT/IGIB during the last 10 years.
1998 - IGIB established largest clinical network in India
2000 - First Knowledge Alliance ‘GenoMed’ with NPIL
2002 - G.N. Ramachandran Knowledge Centre for Genome Informatics established through private funding
to attract IT Professionals
2003 - First Bioinformatics Software of CSIR Commercialized
2004 - Largest Private – Public partnership TCGA “The Centre for Genomic Application” (co-shared facility)
established
2005 - First Genomic marker for drug response discovered
2005 - Largest High Performance Computing facility (4.7 tera flops) established
2005 - India’s highest number of co-authored (158) paper published
2005 - First Recombinant Growth Factor drug REGEN-D launched (Technology Award 2006)
2005 - HP Centre of Excellence in Bioinformatics in Asia.
2005 - IGIB among the World’s best Bioinformatics Institutes for developing PML 2 protocol
2006 - First Bioincubator “Eclosion” being established
2005-06- IGIB attains highest number of paper, total IF, Patents and ECF per scientist
2007 - IGIB coordinated Indian Genome Variation project provided the Genetic landscape of people of India:
A canvas for affordable predictive medicine development and for informed policy level decision for
Adverse Drug Reaction and disease (like HIV,Malaria, Diabetes, CVD etc.) management
2007 - Initiated a novel programme on Open Source Drug Discovery platform for infectious diseases
2007 - Launched a programme on pharmacogenomics to keep affordable drugs in the market.
Visits Abroad
- Participated in workshop on “Chromatin structure”. Weizmann Institute of Sciences. Rehovot, Israel, March 1979.
- Visiting Scientist to Dept. of Biochemistry, Memorial University of Newfoundland, St. Johns Newfoundland, Canada, Nov. 1979.
- Participated in first AMBO meeting on “Future of Nucleic Acid Research” in Kyoto, Japan, Dec, 1981, and visited several laboratories in Japan during 26th Nov. to 22nd Dec, 1981.
- Visitor, University of Ulm, West Germany, May 1985.
- Participation and paper presentation at the IVth conversation in Biomolecular Stereodynamics, Albany, N.Y.USA, June 1985.
- Visiting Scientist, Dept. of Human Genetics and Development, University of Columbia, N.Y. USA, June-Sept. 1985.
- INDO-USSR ILTP exchange visit. Institute of Molecular Biology, USSR Academy of Sciences, Moscow, May 1988.
- Symposium speaker, 6th Convention in Biomolecular Stereodynamics, Albany, N.Y., USA, June 1989.
- Visitor, Dept. of Biochemistry, Oxford University, Oxford, UK, June 1989.
- Visitor, Dept. of Biochemistry, Tufts University, Boston, USA. June 1989.
- Invited, speaker, 2nd International symposium of Protein Structure Functions, University of Karachi, Pakistan, Dec 1989.
- Participated and presented poster at the Gordon Research Conference on “Nuclear Proteins, Chromatin Structure and Gene Regulation” Tilton school, New Hampshire, USA, July 1990.
- Visitor, Dept. of Biology, Massachusetts Institute of Technology, Cambridge, USA, July 1990.
- Participated and presented paper at 10th International Biophysics Congress of IUPAB Vancouver, Canada, 29th July-3rd August 1990.
- Visiting Scientist, Dept. of Molecular Biology, Stanford Research International, Stanford, California, USA, Aug 1990.
- Invited speaker, International Symposium on “Synthetic Oligonucleotides: Problems and Frontiers of Practical Application”, Shemyakin Institute, Moscow, June 1991.
- INDO-USSR ILTP exchange visit. Institute of Molecular Biology, USSR Academy of Sciences, Moscow, July 1991.
- Symposium speaker, 8th Conversation in Biomolecular Stereodynamics, Albany, N.Y., USA, June 1993.
- Visitor, Dept. of Biophysics, University Paris Nord, Paris, France, June 1993 (Hosted by Prof. E. Taillandier).
- Visitor, Dept of Biophysics, Museum National D’Histoire Naturelle, Paris, France, 1993 (Hosted by Prof. C. Helene).
- Visitor, Dept. of Chemistry, New York University, New York University, New York, USA, 1993 (Hosted by Prof. N. R. Kallenbach).
- Visitor, NIDDKD, National Institute of Health, Maryland, USA, 1993 (Hosted by Prof. H. T. Miles).
- Visitor, Dept. of Molecular Biology, National Institute of Health, Maryland, USA, 1993 (Hosted by Dr. S. Adhya).
- Visitor, Dept. of Chemistry, University of Rutgers, New Jersey, USA, 1993 (Hosted by Prof. Wilma Olson).
- Visitor, Dept. of Biology, MIT, Cambridge, Boston, USA, 1993 (Hosted by Prof. A. Rich).
- Visitor, Dept. of Human Genome Centre, Boston University, Cambridge, USA, 1993 (Hosted by Prof. Charles R. Cantor).
- Visitor, NIG, Japan, 1996 (Hosted by Prof. T. Gojobori).
- Visitor, Genome Science Laboratory, Riken, Japan 1996 (Hosted by Dr. Y. Hyashizaki).
- Visitor, Banyu Tsukuba Research Institute, Tsukuba, Japan, 1996 (Hosted by Prof. Susumu Nishimura).
- Visitor, Human Genome Centre, Tokyo, Japan, 1996 (Hosted by Prof. Yoshiyuki Sakaki).
- Invited Speaker, Human Genome Treaty Symposium, Berlin, Germany, October 1996.
- Visitor, Institute of Human Genetic, Berlin, Germany, October, 1996 (Hosted by Prof. Karl Sperling).
- Visitor, Institute fur Kristallagraphie, Germany, October 1996 (Hosted by Prof. W. Saenger).
- Visitor, Max-Planck Inst. fur Biophysical Chem, Germany, October 1996 (Hosted by Prof. T. M. Jovin).
- Visitor, Max-Delbruck Centre for Molecular Medicine, Berlin, Germany October 1996 (Hosted by Dr. U. Heinmann).
- Visitor, Genetique Medicale Et. Development, Marseille, France, October 1996 (Hosted by Prof. M.Fontes).
-
Senior visiting scientist, Max-Planck Inst. for Biophysical Chem. Goettingen, Germany, May-June 1997.
- Attended the council meeting of the FAOBMB & the 8th FAOBMB Congress, Kuala Lumpur, Malaysia, November 1998.
- Attended and delivered invited talk at the Indo-Israel Golden Jubilee Conference, Israel, December 1998-January 1999.
- Attended the Council meeting of the FAOBMB, Delivered invited symposium lecture at 14th FAOBMB Symposium, University of Otago, Dunedin, New Zealand, November 1999.
- Delivered invited lecture at Institute for Biomedical Research, University of Sydney, Sydney, December 1999.
- Attended the International Colloquium entitled “Life Sciences, Ethics, Economy & Society” at University of Bordeaux-I, France, June 2000.
- Attended 2nd Indo –US Round Table Dialogue meeting in Washington DC, September 2000.
- Invited speaker at an International Symposium on “Ethics, Intellectual Property and Genomics” at UNESCO Headquarters, Paris, 30th January-1st February 2001.
- Attended and delivered invited talk at the Working Group Meeting as a follow up of the symposium on “Ethics, Intellectual Property and Genomics” at UNESCO Headquarters, Paris, 13th –14th June 2001.
- Attended and delivered invited talk at the Symposium on Bioethics in Austria 21st-23rd November 2001.
- Attended and delivered invited talk at the Conference on Expert Group on Human Rights and Biotechnology at Geneva 23rd – 25th January 2002.
- Invited Speaker for HGM 2002 workshop at Shanghai 14th – 17th April 2002.
- Attended and delivered invited talk at the conference on “Bioscience Asia 2002” at Taiwan 20th – 23 rd May 2002.
- Attended Indo-South African Workshop on advanced computing, organised by Department of Science & Technology at Pretoria, S. Africa, 28-29 October 2002.
- Invited speaker during India Celebrations Day at Royal Society London, 11th Dec 2002
- Participated in a Workshop organised by the University of Mauritius to help them in developing Bioinformatics and its application to Academics and graduate students and also to discuss and identify together with Academics niche research areas in the Bio-informatics field, 18th to 25th October 2003.
- Participated in the 1st Meeting of India-EC Steering Committee at Brussels, Belgium from March 3rd to 5th, 2004.
- Visited Japan at the invitation of Japan External Trade Organization (JETRO)’s Support Programme for Japan- India Business Matching in the Field of Biotechnology from March 21st to 27th, 2004 at delivered invited talk at JETRO.
- Visited Russia as a member of the Indian delegation to Russia to participate in the 12th Session of ILTP Joint Council Meeting in St. Petersburg and Joint Committee Meeting of the Russian-Indian Centre for Ayurvedic Research in Moscow from September 30th to October 4th, 2004.
- Visited Swiss Federal Institute of Technology (EPFL), Lausanne, Switzerland to develop collaborative project under the Indo-Swiss Collaboration Programme to identify promising areas in Life Sciences and for business development during October 5th to 7th, 2004.
- Participated at the HUGO Council meeting at Toronto, Canada on 27th October, 2004.
- Headed the Indian delegation participating in the Sino-Indian Workshop on Genome Informatics held at Hangzhou, China from October 27th to November 2nd, 2004.
- Invited speaker at the HUGO Pacific Meeting in Singapore November 17-20, 2004 and took part in the Pan Asian SNP Consortium meeting in Singapore on 18th November, 2004.
- Invited speaker, Council Member and the Chairman of the Fellowship Committee at the FAOBMB/IUBMB/A-IMBN Meeting held at Bangkok, Thailand from 22nd to 26th November, 2004.
- Invited speaker at the International Conference Asia Biotech Forum 2005 at Kuala Lumpur from 3rd to 4th February, 2005.
- Invited speaker at the Workshop entitled “Health of Populations in the Mediterranean in the post genomic era” in Tunisia from 4th to 5th March, 2005.
- Attend the India Pharma Fund Limited inaugural board meeting at Mauritius on 17th March, 2005.
- Delivered an invited talk at the HUGO’s Tenth International Human Genome Meeting, HGM2005, Kyoto, Japan, from 18th to 21st April, 2005 and took part in the Pan Asian SNP Initiative Executive Committee Meeting and the Pan-Asia SNP Initiative Policy Review Board (PRB) Meeting.
- Attended and delivered invited talk at the Workshop on “Promoting and Facilitating Innovation driven new ventures”, held fro 29th May to 3rd June, 2005 at Technion – Israel Institute of Technology, Haifa, Israel.
- Invited talk at the Albany 2005: The 14th Conversation at Albany, NY, USA from 14th -18th June,2005.
- Invited talk at the Annual Convention of BIO 2005 in Philadelphia, USA from 19th-21st June 2005 and was a speaker at the CII Session on " India in the wake of 2005: A Hub of Innovation."
- Visited Centre National de la Recherche Scientifique (CNRS), Paris, France from 23rd -25th June 2005 to discuss about possible future collaborations and prepare for joint projects in the area of Integrated Systems Biology for Health.
- Attended the India Pharma Fund Limited board meeting at Mauritius on 4th-5th July 2005.
- Attended and delivered invited talk at the 2005 International Symposium on Computational Biology & Bioinformatics (ISCBB2005) in Tokyo, Japan on 28th October, 2005.
- Delivered invited talk at the meeting on Integrative Systems Biology for Health -TRANSCRIPTOME 2005 at Shanghai, China from 5th -10th November, 2005.
- Attended the India Pharma Fund Limited board meeting at Mauritius on 10th-11th January, 2006.
- Delivered invited talk the Taiwan-India Joint Symposium on Functional Genomics at Taipei, Taiwan on 3rd-4th March, 2006.
- Invited lecture at the HUGO Asia Pacific Meeting held at Taipei, Taiwan from 6th-10th March, 2006.
- Visit and invited talk at the Dept of Bioorganic Chemistry, Uppsala Universitet, Uppsala, Sweden, May 2006 (Hosted by Prof. Jyoti Chattopadhyaya).
- Invited as a Chairman at the Bioinformatics Workshop at HUGO’s Eleventh International Human Genome Meeting, HGM2006 at Helsinki, Finland from 31st May to 3rd June, 2006 and also delivered invited lecture in the EU Workshop on 3rd June, 2006.
- Attended the India Pharma Fund Limited board meeting at Mauritius on 14th June, 2006.
- Invited talk at the Human Variome Project Meeting at Melbourne, Australia from 20th to 23rd June, 2006.
- Invited talk at the 2006 International Conference on Genomics in Hangzhou, China from 23rd – 25th October, 2006.
- Attended the Data Analysis and Manuscript Writing Meeting of the Pan Asian SNP Initiative in Singapore from 9th – 11th November, 2006.
- Attended the 3rd Meeting of the India-EC Steering Committee on S&T Cooperation at Brussels, Belgium on 16th & 17th November, 2006.
- Invited to the 2nd UKIERI (UK-India Education and Research Initiative) Evaluation Panel meeting at London, UK on 28th – 29th November, 2006.
- Visit to the University of Leicester, UK at the invitation of Prof. Anthony Brookes on 1st December, 2006.
- Attended the India Pharma Fund Limited board meeting at Mauritius on 16th January, 2007.
- Attended the Manuscript Writing Meeting of the Pan Asian SNP Initiative in Singapore from 20th – 21st March, 2007.
- Invited as a Chairman at the Bioinformatics Workshop at HUGO’s 12th International Human Genome Meeting, HGM2007 at Montreal, Canada from 21st to 24th May, 2007.
- Visit in USA to Research Triangle Institute International, NC; National Human Genome Research Institute, Bethesda; invited talk at the National Cancer Institute, NIH, Bethesda and Center for Complex Disease, Genomics McKusick - Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore from 25th May to 3rd June, 2007.
- Visit San Francisco, USA to attend the Governing Body meeting of the Indo-US S&T Forum on 12th December, 2007.
- Invited to deliver talk at the "Genesis" Conference, organised by London Biotechnology Network in London from 13th to 15th December, 2008 to deliver the .
- Invited to deliver Plenary talk at the 7th HUGO-AP Meeting at Cebu, Philippines from 2nd to 5th April, 2008.
- Visit to Kuala Lumpur, Malaysia to attend the GRA Principal meeting on 10th & 11th April, 2008.
- Visit to London at British High Commission’s invitation for USA-Indo-S&T Forum 9 December-16 December 2008.
- Visit to Manila, Philippines, HUGO conference 1 April – 6 April 2008.
- Visit to Kuala Lumpur, Malaysia, GRA Meeting, 9 April – 11 April 2008
- Visit to China, China Academy Conference, 11 November-16 November 2008
- Visit to Geneva, Expert Group Meeting of WHO, March 2009
- Visit to Russia to Explore Possibility in the Area of Sustainable Energy, 12th May-20th May 2009
Invited Lectures delivered at various International laboratories, National and International Conferences
- Lectures delivered in National Forum
- Invited speaker, INDO/FRG seminar, Molecular Biology and Agriculture division, BARC Bombay, India, March 1982.
- Invited speaker, Int. Symposium on Genome organisation and Expression in development, Differentiation and Neoplasia, Dept. of Zoology, University of Poona, Pune, Feb. 1984.
- Invited speaker, Int. Symposium On Biomolecular structure and interactions, IISc. Bangalore, Dec. 1984.
- Invited Speaker, XII Annual meeting of Indian Biophysical society, Dept. of Biochemistry, University of Mysore, Mysore, Feb. 1985.
- Invited Speaker, 54th Annual meeting of the Society of Biological Chemists, Panthnagar, India, Nov. 1985.
- Invited speaker, Int. Symposium on Immunochemistry, Structure and Function of Nucleic Acids, IISc., Bangalore, July 1987
- Invited speaker, Mahabaleshwar Seminar in Modern Biology on “Molecular Evolution”, Oct. 1987.
- Invited speaker, Symposium of Genetic Engineering Research in India, IISc. Bangalore, July 1988.
- Invited speaker, INDO-SOVIET symposium on Genetic Engineering, IICB, Calcutta, March 1989.
- Invited speaker, International symposium on Bioseparation, CSIR Centre for Biochemicals, New Delhi, December 1989.
- Guha Research Conference, Lakshadweep, India, 9th-13th January 1990.
- Symposium speaker, INDO-SOVIET workshop on “DNA-Protein interaction and cross-linking” Bangalore, India. 21st-25th March 1990.
- Invited Speaker, National Symposium on Biophysics, Madras, February 1991.
- Guha Research Conference, Udaipur, India, March 1991.
- Invited speaker, 57th Annual Meeting of the Academy, Pune, November 1991.
- Invited speaker, “Gene Structure and Expression” symposium, IISc, Bangalore, December 1991.
- Guha Research Conference, Kemmangundi, India, December 1991.
- Invited speaker, Diamond Jubilee Annual General Body Meeting, Society of Biological Chemistry, Calcutta, December 1991.
- Invited speaker, “Regulation of Gene Expression” Nagarbhavi, Bangalore, January 1992.
- Dept. of Anatomy, All India Institute of Medical Sciences, New Delhi, India, Feb 24th-6th March 1992.
- Dept. of Biotechnology (India), Extension Lecture, Dept. of Biochemistry, Gulbarga University, Gulbarga, India, July 1992.
- Symposium speaker, Trends in DNA Structure-Function and Genome Organization, 11th-14th Jan, Bangalore, 1993.
- Invited speaker, “Biophysics Symposium”, Calcutta, February 1993.
- Guha Research Conference, Dalhousie, India, May 1993.
- Invited speaker, “International Symposium on Cellular & Molecular Aspects of Developmental Regulation” Pune, November 1993.
- Invited speaker, “INSA Golden Jubilee Symposium” Delhi, January 1994.
- Invited speaker, “Symposium on Bioinformatics: The current scenario”, Calcutta, 1994.
- Invited speaker, “Gene Therapy”, Delhi, September 1994.
- Symposium speaker, 16th International Congress of Biochemistry and Molecular Biology, Delhi, September 1994.
- Symposium speaker, Asian Conference on Transcription (ACT III), Bangalore, September 1994.
- Invited speaker, “Emerging Areas in Science and Technology”, Jorhat, October 1995.
- Symposium speaker, “Third International Symposium on Genetics, Health and Disease”. Amritsar, December 1995.
- Symposium speaker, “South-North Human Genome Conference”, Delhi December 1995.
- Symposium speaker,” Genome Analysis: Recent Trends and Applications”, Hyderabad, Jan. 1996
- Invited speaker, “Genome 96: Workshop on Biotechnology”, Bangalore, January 1996.
- Invited speaker, “Transcription Assembly”, Hyderabad, August 1996.
- Invited speaker, Society of Biological Chemists, Bangalore, Sept. 1996.
- Symposium speaker, “MBU Silver Jubilee Symposium on Structural Biology”, Bangalore, Dec. 1996.
- Guha Research Conference, Mirik, India, December 1996.
- AP Mitra Memorial Lecture, Dept. of Chemistry, Delhi Univ., Delhi, September, 1997
- Diversity in Modern Biology – An Interdisciplinary Symposium, University of Delhi, South Campus, N.Delhi, September, 1997.
- International Hands-on Training Course on DNA Fingerprinting, CCMB Hyderabad, India, November, 1997.
- 46th Annual Conference of Neurological society of India, Jaipur, India, December 1997.
- Dept. of Anthropology, Univ. of Delhi, Delhi, December 1997.
- 49th Indian Pharmaceutical Congress, Thiruvanthapuram, India, December 1997.
- Anniversary meeting of INSA, Hyderabad Univ., Hyderabad, India, December 1997.
- Winter school on Human Genetics, I.S.I., Calcutta, January, 1998.
- Second annual National Convention of ADNAT, CCMB Hyderabad, March 1998.
- National Defence College, New Delhi, March 1998.
- Jawahar Lal Nehru University, New Delhi, March 1998.
- Vision for Neurosciences in next millennium, Indian Habitat Centre, New Delhi, March 1998.
- Seminar on Science & Technology-21st century challenges (ST-2000), Jamia Millia Islamia, New Delhi, March 1998.
- Indo-French Workshop on new Opportunities in Molecular Technologies, Ashoka Hotel, Bangalore, March 1998.
- Frontiers in Biomedical Research, Ambedkar Centre for Biomedical Research, University of Delhi, Delhi, April 1998.
- All India Institute of Medical Sciences, New Delhi, April 1998.
- Director’s Conference, NAL, Bangalore, May 1998.
- National Academy of Sciences, Allahabad 1998.
- St. Stephen’s College, Delhi, September 1998.
- Delhi University, Botanical Society, Dept. of Botany, Delhi University, Delhi.
- 5th Annual Symposium Ranbaxy Science Foundation, Gurgaon, NII, New Delhi, October, 1998.
- International Update on Neurosciences, All India Institute of Medical Sciences, New Delhi, November 1998.
- Workshop on Sequence Analysis & Molecular Modelling, School of Life Sciences, Jawahar Lal Nehru University, New Delhi, December 1998.
- 67th Annual Meeting of Society of Biological Chemists (I), School of Life Sciences, Jawahar Lal Nehru University, New Delhi, December, 1998.
- 86th Session of the Indian Science Congress Association, Anna University, Chennai, January 1999.
- Workshop on “DNA Isolation from Forensic Specimen & STRs analysis”, Central Forensic Science Laboratory, Calcutta, March 14-26, 1999.
- Golden Jubilee Celebrations, VP Chest Inst. Delhi, April 1999.
- Symposium on Research in Molecular Biology and Biotechnology in India: Challenges in the next millennium, India Institute of Chemical Biology, Calcutta, September 1999.
- National Symposium on Bimolecular Electronics-Interfacing Physics and Chemistry with Biology, National Physics Laboratory, New Delhi, September 1999.
- Sixty fifth Annual meeting, Indian Academy of Sciences, CDRI, Lucknow, October 29-31, 1999.
- Trends in Biochemistry, Sixth meeting, Department of Biotechnology, University of Delhi, New Delhi, November 23-24, 1999.
- Invited lecture at Miranda House College, Delhi, December 1999.
- 68th Annual Meeting of SBC (I) & Symposium on Current Trends in Biology, Indian Institute of Science, Bangalore, December 27-29, 1999.
- Millennium Lecture at 87th Science Congress in Plenary Session Emerging Frontiers in Basic Science and Technology, Pune, Jan 4th 2000.
- Symposium on Impact of Science on Society in next Millennium at Vivekananda Institute of Medical Sciences, Calcutta, 7th Jan 2000.
- Invited lecture at National Aerospace Laboratories Bangalore, July 20th, 2000.
- Seminar on Beyond Genome- Bioinformatics and Drug Research, CII, Delhi, July 25th 2000.
- Seminar on Developing India’s Capability In Genomics: New Era of Public – Private Partnership in Genomics IT & Medicine, FICCI, New Delhi, July 26th 2000.
- Seminar on Beyond Genome- Relevance for India, CII, Delhi, July 25th 2000.
- Colloquium on The Human Genome: Scientific and Ethical Implications, Centre for Philosophy and Foundations of Science, New Delhi, August 7th, 2000.
- Invited lecture at the Training Programme for Senior IAS Officers, Lal Bahadur Shastri National Academy of Administration, Mussoorie, 17th August 2000.
- Invited lecture at Defence Science Forum, Metcalfe House, Delhi, August 24th 2000.
- Invited lecture at Kirori Mal College, Delhi, 27th September 2000.
- INDO-CUBA Workshop on Biotechnology in health care, INMAS, Delhi, 3rd October 2000.
- Seminar on India Chem 2000 Conference, FICCI, New Delhi, 6th October 2000.
- Invited lecture during the Biotechnology Conference organised by Chemtech Foundation, Mumbai, 10th November 2000.
- Invited lecture on 5th International meeting on “Molecular Epidemiology and Evolutionary Genetics of Infectious diseases”, CDFD, Hyderabad, 14th November 2000
- Invited lecture at Daulat Ram College, Delhi, 16th November 2000.
- Invited lecture at National Science Centre during the symposium Biotechnology India 2000 organised by Exhibitions India Pvt. Ltd, 29 November 2000.
- Invited lecture at International Workshop on “Innovation in Science and Technology: Economic, philosophical and social dimensions” held at CSIR Science Centre, organized by NISTADS, 5th December 2000.
- Delivered lecture at Indian Institute of Chemical Biology, Calcutta during the 69th Annual meeting of the Society of Biological Chemists (India), 8th December 2000.
- Invited lecture at Chembiotech, Calcutta during the symposium Chemcon 2000, 19th December 2000.
- Seminar on “Haemoglobinopathies-South Asia-Problems and Prevention” at Vivekananda Institute of Medical Sciences, Calcutta, 29th December 2000.
- Invited lecture at J. N. Tata Auditorium, National Science Seminar Complex, IIS Campus Bangalore organised Confederation of Indian Industry, India, 16th January 2001.
- Invited lecture on “Information Technology & Biotechnology: Bridge over Genome River at M. S. Ramaiah School of Advanced Studies, Bangalore 17th January 2001.
- Delivered a lecture at Chemistry Society Hindu College, Delhi University, 24th January 2001
- Delivered a lecture on “DNA Microarray Technology” Workshop at IISc Bangalore, 19th February 2001.
- Delivered a lecture in the “ISHG-2001” XXVI Annual Conference of the Indian Society of Human Genetics at CCMB Hyderabad, 21st February 2001.
- Delivered a lecture in the Workshop cum Seminar on Bioinformatics during the national symposium – Biohorizon 2001 at IIT, Delhi, 24th February 2001.
- Delivered a lecture during the national Conference on “Human Genome-The Prospective Research Strategies” at Post Graduate Institute of Medical Education & Research, Chandigarh, 24th-25th August 2001.
- Delivered a lecture at the meeting on “Biomolecular Conformation and Function” at Indian Institute of Science, Bangalore, 26th July 2001.
- Delivered a lecture on “The Human Genome Research and its Social Implications” at Indian Agricultural Research Institute, New Delhi, 29th August 2001.
- Round Table Discussion on Genomics, IISc Bangalore, 3rd September 2001.
- “Population Polymorphism Scanning: A functional genomics approach”, for the society young Scientist at AIIMS at 7th September 2001.
- INDO GERMAN Symposium on Genomics at Chandigarh 18th September 2001.
- Delivered three Lectures at IIT, Kanpur: “Functional Genomics in silico”, “Population Polymorphism Scanning: A Novel method for Gene Function Discovery” and “Public Lecture: Beyond the Human Genome Sequence”. 15th – 16th October 2001.
- Delivered a Talk at MV Symposium, IISc Bangalore, on PLHOSTFA novel tool for identification of Functional signatures and Comparative genomics 22nd – 29th November 2001.
- “DNA Microarray opportunities and Challenges ahead”, at Mini-symposium ICGEB, New Delhi. 30th November 2001.
- Delivered a Lecture at Workshop on Functional Genomics at ISI, Kolkata. 11th December 2001.
- Delivered a talk on “Genomics and New Drug Discovery” at Goa. 15th December 2001.
- Delivered a talk “BT-IT: Bridge over River Genome” at Techfest, IIT- Mumbai.2nd February 2002.
- Delivered a talk on “BT-IT: Bridge over River Genome” at IIT, Kharagpur. 11th February 2002.
- Delivered a Lecture “PLHOSTFA novel tool for identification of Functional signatures and Comparative genomics at ADNAT Symposium CCMB, Hyderabad. 23rd February 2002.
- Delivered a talk on “Population Polymorphism Scanning: A Functional Genomics approach at INDO French workshop INSA on 4th March 2002.
- Delivered lecture during the Pharmacogenomics meeting at DBT on July 11th 2002.
- Delivered an invited lecture at Regional Research Laboratory, Trivandrum on Beyond the Human Genome Sequence: Predictive and Personalised Medicine” on November 22th 2002.
- Delivered lecture at CCMB, Hyderabad on “Comparative and Functional Genomics In silico” in the International Knowledge Millennium Conference at the Symposium `The Current Excitement in Biology’ on November 24-29th 2002.
- Delivered a talk on “Comparative and Functional Genomics: New opportunities and Challenges” at Bundelkhand University, Jhansi during the `Emerging Areas in Biomedical Sciences’ on December 28-30th, 2002.
- Delivered invited lecture in the celebration of `50 years of DNA Double Helix’ at Guru Gobind Singh Indraprastha University on the topic “From Helix to Genomics – A 50 year Saga” on January 11th, 2003.
- Delivered lecture during the Workshop `Knowledge Discovery in Genomics & Proteomics Bio informatics Approach’ at Pune University on January 15th, 2003.
- Delivered lecture on `The Need for Grand Vision and Microplanning’ at CIMAP Lucknow during the Annual Meeting of Planning and Business Development Scientists on January 22-23th, 2003.
- Delivered lecture Title: “B.K. Bachhawat Memorial Lecture” during the Symposium `Frontiers in Molecular Medicine’ at Jawahar Lal Nehru University on February 10th, 2003.
- Delivered lecture Title: “Comparative Genomics: An Approach to Seamless Biology” during the Yeast 2003 Symposium at IMT in March 2003.
- Delivered lecture on "Human Genome Project" at the Shaheed Rajguru College of Applied Sciences for Women, Univ. of Delhi on February 26th, 2003
- Delivered lecture on `Beyond the Human Genome Sequence: Predictive and Personalized Medicine’ in DIPAS, Delhi on February 28th, 2003.
- Delivered lecture on 23.3.03 during the Knowledge Millennium III- the Business of Biotechnology organised by ASSOCHAM during March 21-23th, 2003.
- Delivered lecture on “Showcasing Institutional R&D: IGIB” in Bangalore Bio 2003 on April, 2003.
- Delivered Dr. C. R. Krishnamurthy Award lecture at CDRI, Lucknow on March 4th, 2003
- Delivered lecture in a symposium on “Genomics: Challenges and opportunities, at Hyderabad on April, 2003
- Delivered lecture during workshop on "Genetic Epidemiological Methods for dissection of complex human traits" at ISI, Kolkata on 11 June 2003.
- Delivered lecture at Miranda House, Delhi University on "Borderless Science: Integration of Biology, Chemistry and Information Technology", on Sep 22nd 2003.
- Delivered lecture on Role of Bioinformatics in Genomics" in Symposium "Computational challenges in Bioinformatics" at C-DAC, Pune on 5th Nov 2004.
- Delivered lecture on "SNPs, Chips, Informatics and Predictive Medicine" at ITRC, Lucknow on 7th Nov 2003.
- Delivered Talk on "IPR & PPP In Biotechnology" on 17th Nov 2003 at TERI Retreat, Delhi.
- Delivered lecture at Sri Venkateswara College, Delhi University on "Borderless Science: Integration of Biology, Chemistry and Information Technology", on Nov 26th 2003.
- Delivered lecture at FAOBMB Symposium at IGIB, on "Variation and Conservation: a balancing act in genome" on 6th Dec 2003.
- Delivered lecture on "Functional Genomics to System Biology: Integration of Information Technology to biology" at Indian Science Congress, 3-7 Jan 2004, Chandigarh.
- Delivered lecture on "Functional Genomics to System Biology: Integration of Information Technology to biology" at All India Cell Biology Conference & International Symposium, Pune on Jan 9th 2004.
- Delivered talk on "Globalization of Biotech R&D: Role of Indian Institutions" in CII conference "BioEconomy-Growth Engine of 21st century" on 5th Feb 2004.
- Delivered talk on "New Horizons in BioTechnology - Planning for the Century" at TIFAC, Delhi on 10th Feb 2004.
- Delivered talk on "Challenge of Managing Creativity" at TERI Retreat, Delhi on 11th Feb 2004.
- Delivered talk on “Three Decades @MBU: Triple Helix to Genomics” at Molecular Biophysics Unit, Indian Institute of Science, Bangalore on 29th April, 2004
- Delivered inaugural and keynote lecture at Indo-Tunisian Workshop on Bioinformatics in Medicine on 28th June, 2004 at Delhi on “Predictive Medicine in Genomic Era”.
- Delivered a lecture on “Beyond the Human Genome Sequence” at Kulachi Hansraj Model School, Delhi on 28th June 2004.
- Delivered 14th G.S.Sidhu Science Lecture at IICT, Hyderabad on 2nd July 2004 on “SNPs, Chips, Informatics and Predictive Medicine”.
- Talk on “Public – Private Partnership in Biotech R&D” at IIM, Ahmedabad on July 3rd, 2004.
- Invited lecture at 4th Management Development Programme on harnessing Intellectual Property for Strategic Competitive Advantage on July 3rd 2004 at IIM, Ahmedabad on “IP Mediated technology collaboration between public and private sector”.
- Delivered talk at Bangalore Bio 2004 on 12th July 2004 in the session ‘Current Advances in Biotechnological Session’ on “Functional Genomics to System Biology- Integration of Information Technology to Biology”.
- Delivered plenary talk “Predictive Medicine in Genomic Era” at Indo-Tunisian Workshop on Bioinformatics in Medicine, New Delhi on 28 June 2004.
- Delivered invited lecture on “SNPS, Chips, Informatics and Predictive Medicine” at “Genomics 2004: Challenges and opportunities” organised by National Centre for Plant Genome Research, Delhi on 13th September, 2004.
- Delivered talk on “Science and Business of Bioinformatics: Will India Lead or Follow?” at Centre for DNA Fingerprinting and Diagnostics, Hyderabad on 14th September 2004.
- Delivered lecture as faculty of the INSA sponsored workshop on Genomics and Medicine at University College of Medical Sciences, Delhi on 23rd September, 2004.
- Delivered talk on “Public – Private Partnership in Biotech R&D Opportunities in Life Sciences” at Technology Summit & Technology Platform 2004, organised by CII in Delhi on 19th October, 2004.
- Delivered Invited Lecture on “ “Dare to Dream & Dream to Dare”: Need for sustained Commitment to Implement Dreams” at CII Conference “Building Innovative Pharma in India” on 5th Nov 2004 in New Delhi at the Session “Branding India-The Hub of Innovation”.
- Delivered an invited talk at the session on IITians Empowering India: Global Competitiveness: Bio- technology at the pan IIT meet on the 24th December 2004, entitled “Global Competitiveness in Biotechnology: Need for Innovation” held at Delhi.
- Chaired the session ‘Indian Goal in Genomics’ and delivered a talk on 6th January, 2005 at the 92nd Session of Indian Science Congress held at Ahmedabad, entitled “Genomics to System Biology: An Overview”.
- Delivered an invited lecture at Indian Statistical Institute, Kolkata on 17th January, 2005 on “Genome Research: Where do we stand?”
- Delivered an invited talk at the International Conference ‘50 years of discovery of triple “Triple Helix to Comparative Proteomics” organised by University of Pune.
- Delivered an invited lecture at the Ramanbhai Foundation 2nd International Symposium at Ahmedabad titled “Comparative Proteomics in silico for Drug Target Identification” on 24th January, 2005.
- Delivered invited talk at the International Conference, BioAsia 2005 in Hyderabad at the Student Forum entitled “Global Competitiveness in Biotechnology: Need for Innovation” on 10th February, 2005.
- Delivered a talk at International Symposium on “Genes, Evolution and Complex Diseases” at NCBS, Bangalore on 19th February, 2005 at the Session “Bioinformatics approaches to the study of complex diseases”: “Schizophrenia as a Case Study”.
- Delivered an invited talk at the ADNAT Convention / Symposium on Molecular Medicine and Health in Hyderabad on 20th February 2005 entitled “Comparative Proteomics for Drug Target Identification”.
- Invited as ten Chief Guest at the Book Release Ceremony ‘Microorganisms: Their Biotechnological Applications’ on May 9th, 2005 at AMITY Campus, Noida and delivered a talk entitled “Predictive Medicine and Health Research in the Post-Genomic Era”.
- Delivered an invited talk at the 11th Technology Summit & Technology Platform organized by CII, New Delhi on 21st September, entitled “Indian Biotech at the Crossroads of Development”.
- Delivered an invited talk at the Symposium “Drug Discovery to Clinical Trials” at Mumbai entitled “Current status of India's strengths capabilities in early stage research” on 6th October, 2005.
- Delivered a plenary lecture at the Conference Molecular Mechanism of Diseases and Drug Action (MMDDA 2005) at Saha Institute of Nuclear Physics, Kolkata on 16th November, 2005 entitled “Novel Genomic approaches to understand complex disorders & host pathogen interaction”.
- Delivered an invited talk entitled “The Security Dimensions in Biological Research” at the NISDA Security Conference 2005 “Conceptualizing Security in the 21st Century" on 19th November, 2005 at Pune.
- Delivered invited talk at the session ‘Bio Technology: Translating R&D into Commercial Opportunities’ at the INFOCOM 2005, Kolkata entitled “Leveraging Indian IT for Global Drug Development” on 8th December, 2005.
- Delivered an invited talk at the Annual Festival of the Chemistry Society of the St. Stephen’s College, Delhi University titled “Comparative Genomics and Pathway Modeling approaches towards Novel Drug Target Identification’ on 22nd December, 2005.
- Delivered the Kapil Sood Oration at the UP NEUROCON, organized by the Fortis Hospitals titled “Predictive Medicine- from Bench to Bedside” on 26th February, 2006 at Noida.
- Delivered a talk titled “Keeping up with the Expectation in Science!” at the Symposium Frontiers of Molecular Biology in the New Millennium at Jawaharlal Nehru University, New Delhi on 12th April., 2006.
- Delivered the inaugural, keynote address at the Consultative Meeting on National Innovation Systems (NIS) of India entitled “Innovation Systems for R&D in Genomics” on 19th September, 2006 at New Delhi organized by United Nations Asian and Pacific Centre for Transfer of Technology, DSIR, CDC and NRDC.
- Delivered invited talk at the International meeting on RNAi at ICGEB, New Delhi 06 entitled “MicroRNA mediated regulatory networks: an in-silico approach” on 27th October 20.
- Delivered a talk at the Jagadis Bose National Science Talent Search (JBNSTS) Science Camp entitled “Joy of Doing Science: Learning vs. Creativity” on 21st November, 2006 at Kolkata.
- Delivered an invited lecture at the 2nd Global Conference and Exhibition on “India R&D 2006- Mind to Market” organized jointly by FICCI and DST entitled “Positioning For The Future : Need For Innovation” on 5th December, 2006 at New Delhi.
- Delivered an invited lecture at the EMBO International Workshop on Human Evolution and Disease at Hyderabad on 7th December, 2007 entitled “Genotype to Phenotype for Complex Disorders: An Integrative Biology Approach”.
- Delivered an invited plenary lecture at the International Winter School on Bioinformatics organized by University of Hyderabad in Hyderabad entitled “Genome Informatics: Opportunities and Challenges Ahead” on 8th December, 2006.
- Delivered an invited talk at session on ‘Beyond Human Genome’ during the 75th Meeting of the Society for Biological Chemists (SBC), India titled “Harvesting the Human Genome Sequence: Need for an Integrative Approach” at New Delhi on 11th December, 2006.
- Delivered an invited talk in the National Science Festival organized by St. Stephens College, Delhi titled “Becoming of a Scientist: Learning vs. Creativity” on 20th December, 2006.
- Delivered an invited talk at the International seminar on Innovation, Creativity and Enterprise organized by University of Mumbai, Institute of Chemical Technology titled “Innovation lead Institutional Transformation: A Case Study” on 24th December, 2006 at Mumbai.
- Delivered the Endowment Lecture [Professor P. K. Bose Memorial Lecture for the year 2004] at the 43rd Annual Convention of Chemists held in the Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad on 25th December, 2006 entitled “Chemistry to Genomics: A Challenging Journey”.
- Delivered the valedictory lecture at the XXXII Annual Conference of ISHG, and International Symposium on 'Deconstructing Human Diseases: The Genomic Advantage' at Kolkata on 16th February, 2007 entitled “Human Genome Research: Road Ahead”.
- Delivered the National Science Day Lecture organized by Indian National Science Academy (INSA), New Delhi on 28th February, 2007 titled “IT for New Biology : Future Challenges“.
- Delivered an invited talk at the International High Performance Computing (HPC) Users Conference on Leadership Computing for Science and Industry organized at Indian Institute of Science, Bangalore titled “Human Genome Research: Computational Challenges Ahead” on 2nd March, 2007.
- Delivered an invited talk at the National Symposium on Current Trends in Zoological Research organized by Presidency College, Kolkata titled “IT for New Biology : Future Challenges” on 10th March, 2007.
- Delivered an invited talk at the National Conference on Health Care Biotechnologyin Bangalore titled “Genome Sequence to Molecular Medicine: The Pharma Business vs. Affordable Health for All” on 21st April, 2007.
- Delivered an invited talk at the International Symposium on Chromosomes to Genome organized by Centre for Cellular and Molecular Biology (CCMB) on 4th July 2007 titled “Looking for Disease Genes: Whole Genome Association Studies vs. Systems Biology Approach“.
- Delivered the Prof. G. N. Ramachandran Oration lecture at the Bioinformatics Centre, University of Pune on 1st August, 2007 titled “Tale of Two Cities: Hope and Reality“.
- Delivered an invited talk at the Biotechnology Seminar organized by Modern School, Vasant Vihar, New Delhi titled “IT for New Biology: Future Challenges” on 1st September, 2007.
- Delivered the Foundation Day lecture of Birbal Sahni Institute of Palaeobotany, Lucknow titled “Human Genome Research: Road Ahead” on 10th September, 2007.
- Delivered an invited lecture at the 5th Global Knowledge Millennium Summit: B2B in Biotechnology & Nanotechnology” organized by ASSOCHAM, Delhi titled “Open Source Drug Discovery: a solution for Infectious Diseases” on 19th September, 2007.
- Delivered the inaugural talk at the Symposium on Problems of Chronic Anemias in India: genetics and Environment organized by Vivekananda Institute of Medical Sciences, Kolkata titled “Human Genome Variome Project: Hope and reality” on 30th November, 2007.
- Delivered an invited talk at the INSA-CAS workshop on structural biology during 21-23 December 2007 at IISc, Bangalore titled “miRNA Mediated novel regulatory networks: an in silico approach”.
- Delivered an invited talk at the Science Commons-drug discovery meeting at IIT Delhi.
- Delivered keynote address titled “Human Genome Variome and Predictive Medicine: Hope & Reality” on the occasion of the Foundation Day of Institute of Life Sciences, Hyderabad on 29th January, 2008.
- Delivered the 15th PC Mahalanobis memorial Lecture during 15th State S&T Congress at Bengal Engineering College, Shibpor, Howrah titled “Tale of 3 cities: Hope and Reality” on 28th February, 2008.
- Delivered an talk titled “Taking Technology from Lab to People” at Indian National Science Academy (INSA), Delhi on 14th March, 2008.
- Delivered Sir gangaram Oration Award Lecture at Sir Gangaram Hospital, New Delhi on 13th April, 2006.
- Delivered the Vision talk at the CEO Conclave during Bangalore Bio 2008 at Bangalore titled “Engineering Bio-systems: beyond the Horizon” on 24th April, 2008.
- First G N Ramachandran Lecture, CAS Crystallography and Biophysics, University of Madras, Chennai. 18th October 2008
- Key note address at PPP Summit 2008 “Nurturing PPP in Life Science Space”, 4th July 2008.
- Valedictory address at NIAS Interactive Session at IISc Campus, 2nd August, 2008.
- Vikram Sarabhai memorial lecture – 2008, 7th August, 2008.
- NEERI Lecture “Importance of Leadership”, 23rd August, 2008.
- Welcome address and CSIR Foundation Day Lecture –know your genome, 26th September, 2008.
- Foundation Day Oration, Rama Krishna Mission, Kolkata “are life scientists trying to play God”, 29th January, 2009.
- A.N. Bhaduri Memorial Lecture, Kolkata, March, 2009.
- Convocation address, Vidyasagar University, 2 April 2009
- Talk delivered Knowledge 2009, All India Management Association, 07 October 2009
- Lectures delivered in International Forum
- National Cancer Research Institute, Tokyo, Japan, Dec.1981.
- Dept. of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, Japan, December 1981 (Hosted by Prof. T. Miyazawa).
- Dept. of Pharmacology, University of Osaka, Japan, Dec. 1981 (Hosted by Prof. M. Ikehara).
- Dept. of Physics, Faculty of Science, University of Tokyo, Japan, Dec. 1981 (Hosted by Prof. A.Wada).
- Section Polymere, University of Ulm, Ulm, West Germany, May 1985 (Hosted by Prof. H. Seliger).
- Centre for Crystallographic Research, Roswell Park Memorial Institute, Buffalo, USA, August 1985 (Hosted by Prof. R. Parthasarathy).
- Dept. of Biophysics and Dept. of Human Genetics, University of Colombia, N.Y. USA, Sept. 1985 (Hosted by Prof. C. R. Cantor).
- Dept. of Biology, Massachusetts Institute of Technology, Cambridge, USA, Sept.1985 (Hosted by Prof. A. Rich).
- Chromosoma Lecture, Institute of Molecular Biology, USSR Academy of Sciences, Moscow May 1988 (Hosted by Acad. A. D. Mirzabekov).
- Institute of Molecular Genetics, USSR Academy of Sciences, Moscow May 1988 (Hosted by Prof Frank Kamaenestkii).
- Dept. of Biochemistry, Tufts University, Boston, USA June 1989 (Hosted by Prof. B.D.Stollar).
- Dept. of Biology, Massachusetts Institute of Technology, Cambridge, USA June 1989 (Hosted by Prof. A. Rich).
- Symposium speaker, 6th Conversation in Biomolecular Stereodynamics, Albany, N.Y. USA, June 1989.
- Invited speaker, 2nd International symposium of Protein Structure Functions, University of Karachi, Pakistan, December 1989.
- Dept. of Biology, Massachusetts Institute of Technology, Cambridge, USA, July, 1990. (Hosted by Prof. A. Rich)
- Dept. of Genetics, University of Washington, Seattle, USA, Aug 1990 (Hosted by Prof. Stanley Gartler).
- Invited speaker, International Symposium on “Synthetic Oligonucleotides: Problems and Frontiers of Practical Application”. Shemyakin Institute, Moscow, June 1991.
- Institute of Molecular Biology, USSR Academy of Sciences, Moscow, June 1991 (Hosted by Acad, A.D. Mirzabekov).
- Institute of Molecular Genetics, USSR Academy of Sciences, Moscow, June 1991 (Hosted by Prof Frank Kamaenestkii).
- Institute of Cytogenetics, USSR Academy of Sciences, Leningrad June 1991.
- Symposium speaker, 8th Conversation in Biomolecular Stereodynamics, Albany, New York, USA 1993.
- Dept. of Biophysics, University Paris Nord, Paris, France, June 1993 (Hosted by Prof. C. Helen).
- Dept. of Biophysics, Museum National D’Histoire Naturelle, Paris, France, 1993 (Hosted by Prof. C. Helene).
- Dept. of Chemistry, New York University, New York, USA, 1993 (Hosted by Prof. N.R. Kallenbach).
- Dept. of Molecular Biology, National Institute of Health, Maryland, USA, 1993 (Hosted by S. Adhya).
- Dept. of Chemistry, University of Rutgers, New Jersey, USA, 1993 (Hosted by Prof. Wilma Olson).
- Dept. of Biology, MIT, Cambridge, Boston, USA, 1993 (Hosted by Prof. A. Rich).
- Dept. of Human Genome Centre, Boston University, Cambridge, USA, 1993 (Hosted by Prof. Charles R. Cantor).
- Invited speaker, 2nd Indo-Japan Workshop and ACT IV meeting Japan, March 1996.
- National Institute of Genetics, Mashima, Japan, March 1996 (Hosted by Prof. T. Gojobori).
- Banyu Tsukuba Research Institute, Tsukuba, Japan, March 1996 (Hosted by Prof. Susuma Nishimura).
- Invited speaker, “Human Genome Treaty Symposium, Berlin, Germany, October 1996.
- Institute of Human Genetic, Berlin, Germany, October 1996 (Hosted by Prof. Karl Sperling).
- Institute for Kristallagraphie, Germany, October 1996 (Hosted by Prof. W. Saenger).
- Max-Planck Inst. fur Biophysical Chem, Germany, October 1996 (Hosted by Prof. T.M. Jovin).
- Max-Delbruck Centre for Molecular Medicine, Berlin, Germany, (Hosted by Dr. U. Heinmann).
- Genetique Medicale Et Development, Marseille, France, October 1996 (Hosted by Prof. M. Fontes).
- FAOBMB 14th Symposium, University of Otago, Dunedin, New Zealand, November 28th –December 3rd 1999.
- Invited lecture, Institute of Biomedical Research, University of Sydney, December 1999.
- Delivered a talk at UNESCO on “Genome Research & IPR” 13th June, 2001.
- Delivered a talk at Vienna on “Genome Research & Patenting in Developing Countries” on 22nd November 2001.
- Delivered a talk at Geneva on Rights & Issues relating to the “Genetic Resources of the Developing Countries” on 24th January 2002.
- Delivered a talk in “Disease Genomics Workshop” at HUGO meeting at Shanghai, April 2002.
- Invited Lecture at Beijing in Genome Centre on April 2002.
- Delivered an invited Lecture in Bioscience Asia meeting at Taiwan on “Functional Genomics in Silico” on 22nd May, 2002.
- Delivered lecture during the India Day Celebrations at Royal Society, London on December 11th, 2002.
- Delivered talk on “Variation and Conservation Balancing Act in Genome: Comparative Genomics Approach” at RIKEN, Japan on 22nd April, 2004.
- Delivered talk on “BT-IT Bridges over Genome River: Functional Genomics to System Biology” at India Biotechnology Seminar in Japan on 23rd April, 2004.
- Delivered a talk “SNPs, Chips, Informatics and Predictive Medicine” at Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland on 6th October 2004.
- Delivered talk on “Variation and conservation: a balancing act in genome” at the Sino-India Workshop on genome Informatics at Hangzhou, China on 30th October, 2004.
- Delivered a talk at the Pan Asian SNP Consortium meeting held at Singapore on 18th November entitled “A brief comment on Pan Asian SNP Project”.
- Delivered invited talk at the 17th FAOBMB/IUBMB/A-IMBN Meeting entitled “Comparative Proteomics in silico for drug target identification” held at Bangkok, Thailand from 22nd to 26th November, 2004.
- Delivered invited lecture at the Asia Biotech Forum 2005 at Kuala Lumpur titled “Private-Public Partnership in Genomics & Bioinformatics: An Indian Perspective” on 4th February 2005.
- Delivered inaugural and keynote address at the Workshop “Health of Populations in the Mediterranean in the post genomic era” in Tunisia on 4th March, 2005 entitled “Predictive Medicine and Health Research in the Post Genomic Era”.
- Delivered an invited talk at the HGM 2005, held at Kyoto on 19th April, 2005 entitled “Conservation and Variation: A Balancing Act in the Genome”.
- Delivered talk on "Identification of Evolutionarily Conserved Polypeptide folds by Comparative Genomics" at Institute of Evolution, University of Haifa, Israel on 29th May, 2005.
- Delivered talk entitled “Transforming CSIR to Council for Scientific & Innovative Research” at the Workshop on “Promoting and Facilitating Innovation driven new ventures” in Haifa, Israel on 31st May, 2005.
- Delivered the BIGROC Lecture at Weizmann Institute of Science, Rehovot, Israel on 2nd June, 2005 entitled “Conservation and Variation: A Balancing Act in the Genome”.
- Delivered an invited talk at session on Comparative genomics in the Albany 2005: The 14th Conversation at Albany, NY, USA entitled “Conservation and Variation: A Balancing Act in the Genome”.
- Delivered an invited talk at the CII session ‘Enabling Global Drug Discovery by Leveraging Information Technology prowess in India’ at the BIO 2005 in Philadelphia, USA on 21st June 2005 entitled "Identification of Novel Drug Targets using In Silico Comparative Genomics and System Biology Approach".
- Delivered an invited talk entitled "Comparative Genomics and pathway modeling approaches towards Novel Drug Target Identification" at the India session at the 2005 International Symposium on Computational Biology & Bioinformatics (ISCBB2005) in Tokyo, Japan on 28th October, 2005.
- Invited to co-chair the session on "Developing the Proper Context for Systems Biology" and deliver a talk entitled “Need for High Input Biology for Systems Biology Approach” at the meeting on Integrative Systems Biology for Health -TRANSCRIPTOME 2005 at Shanghai on 9th November, 2005.
- Delivered a talk at the Taiwan-India Joint Symposium on Functional Genomics at Taipei, Taiwan on 3rd-4th March, 2006 titled Comparative Genomics and Pathway Modelling approaches towards Novel Drug Target Identification.
- Co-chaired and delivered a talk at the session “Biobank” at the HUGO Asia Pacific Meeting held at Taipei, Taiwan from 6th-10th March, 2006 titled ‘Indian Genome Variation Database: From a Disease Perspective’.
- Delivered an invited talk at the Department of Bioorganic Chemistry at Uppsala University on 29th May, 2006 entitled “Conservation and Variation in the Genome: A Balancing Act”.
- Chaired the Bioinformatics Workshop at HGM 2006 at Helsinki, Finland on 1st June, 2006 and delivered Workshop overview entitled “Genome Informatics: Opportunities and Challenges ahead”.
- Delivered a talk at the EU Workshop on International Cooperation in Functional Genomics Research during the HGM 2006 at Helsinki, Finland on 3rd June, 2006 entitled “Functional Genomics: Indian Initiative”.
- Delivered an invited talk at the Human Variome Project meeting at the Session on “Relevance to the Emerging World” at Melbourne, Australia on 22nd June, 2006 entitled “Genotype to Phenotype Correlation (G2P) for Complex Disorder”.
- Delivered an invited talk at the session entitled Genomics in Asia during the 2006 International Conference on Genomics in Hangzhou, China on 25th October, 2006 titled “Genome Variation & Disease Genomics: the Indian Initiative”.
- Delivered lectures at the Pan Asian SNP Data Analysis and Manuscript Writing Meeting at Singapore entitled “Pan Asian SNP Initiative: An Anthropological Perspective” and “Structural Polymorphism in Indian Population” on 9th and 11th November, 2006 respectively.
- Chaired the Bioinformatics Workshop at HGM 2007 at Montreal, Canada on 22nd May, 2007 and delivered Workshop overview entitled “Genomics Research: What’s Next”?
- Delivered an invited talk a the National Cancer Center, National Institutes of Health, Bethesda titled “MicroRNA mediated regulatory networks: an in-silico approach” on 31st May, 2007
- Delivered an invited talk at the McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University, Baltimore titled “Indian Genome Variation database from Complex Disease Perspective” on 1st June, 2007.
- Delivered an invited talk at the “Genesis” Conference in London titled “Can Open Source Drug Discovery address global healthcare challenges in infectious diseases?" on 21st December, 2008.
- Delivered a plenary talk at the 7th Human Genome Organization-Pacific Meeting and 8th Asia Pacific Conference on Human Genetics at Cebu, Philippines on 3rd April, 2008 titled miRNA mediated regulatory network and host pathogen interaction".
In addition to these, Prof. Samir K. Brahmachari has delivered several lectures at various other laboratories and academic institutions.
Complete List of Publications
A. Polypeptides and Proteins
- Polypeptide models of Collagen. I. Solution properties of (Gly-Pro-Sar) and (Gly-Sar-Pro)n. V. S. Ananthanaryanan, Samir K. Brahmachari, Rao, S. Rapaka and R. S. Bhatnagar.
Biopolymers (1976) 15(4): 707
- Polypeptide models of Collagen, II. Solution properties of (Pro-Gly-Phe) n.
Samir K. Brahmachari, V.S. Ananthanaryanan, Rao, S. Rapaka and R.S. Bhatnager.
Biopolymers (1978) 17(9): 2096
- Structural investigations on Poly-4-hydroxy-L-proline I.Theoretical studies.
M. Bansal, Samir K. Brahmachari and V. Sasisekharan.
Macromolecules (1979) 12: 19
- Structural investigations on Poly-4-hydroxy-L-proline. II. Physico-chemical and X-ray studies.Samir K. Brahmachari, M. Bansal, V.S.Ananthanaryanan, V. Sasisekharan.
Macromolecules (1978) 12: 23
- Conformational criteria for the enzymatic hydroxylation of proline in collagen.
Samir K. Brahmachari and V.S.Ananthanaryanan.
Curr. Sci.(1978) 47: 107
- b-turns in nascent procollagen are sites of po7st translational enzymatic hydroxylation of proline. Samir K. Brahmachari and V.S.Ananthanaryanan.
Proc. Natl. Acad, Sci. USA, (1979) 76: 5119
- Vacuum Ultraviolet Circular dichroism spectrum of b-turn in solution.
Samir K. Brahmachari, V.S.Ananthanaryanan, J. Brahms, S. Brahms, Rao, S. Rapaka
and R.S. Bhatnagar.
Biochem. Biophys. Res. Comm. (1979) 86: 605
- b-turn conformation of N-acetyl-Pro-Gly-Phe-OH in crystal and solution and its relevance to collagen.
V.S.Ananthanaryanan, Samir K. Brahmachari and M. Vijayan.
Federation Proc. (1980) 39: 1788
- Crystal structure and solution studies on N-acetyle-Pro-Gly- Phe-OH.
Samir K. Brahmachari, V.S.Ananthanaryanan, T.N. Bhat, V. Sudhakar, M. Vijayan, Rao, S. Rapaka and R.S. Bhatnagar.
J.Amer. Chem. Soc. (1981) 103: 1703
- Proline containing b-turns in peptides and proteins. I. Physico-chemical studies on N-acetyl- Pro-Gly-X-OH tri- peptides
Samir K. Brahmachari, V.S.Ananthanaryanan, Rao, S. Rapaka and R.S.Bhatnagar.
Biopolymers (1982) 21: 1208.
- Proline containing b-turns in peptides and proteins. II. Analysis of globular protein data.
V.S.Ananthanaryanan, Samir K. Brahmachari and N.Pattabiraman.
Arch. Biochem. Biophysics (1984) 232: 482
B. Nucleic Acids and Chromatin
- Site and role of the N-terminal fragment of the nucleosomal core histonesin their bind to deoxyribonucleic acid as determined by vibrational spectroscopy.
M. couppez, Santiere, Samir K. Brahmachari, J. Brahms, J. Liquier and E. Taillandier.
Biochemistry (1980) 19: 3358
- B to Z transition in a DNA fibre: The question of handedness of the duplex.
V. Sasiskharan and Samir K. Brahmachari.
Curr. Sci. (1981) 50: 1
- Conformational flexibility of DNA: A theoretical formalism and a few practical applications.
V.Sasisekharan, Manju Bansal, Samir K. Brahmachari and Goutam Gupta.
Biomolecular sterreodynamics, ed. R.H. Sarma, Adenine Press, N.Y. (1981) 1: 123
- Conformation of DNA in chromatin reconstituted from poly(dA-dT) and the cor histones.
S. Brahms, Samir K. Brahmachari, N. Angelier and J.G.Brahms.
Nucleic Acids Res. (1981) 9: 4879
- B to Z transition in DNA and its biological implications.
Samir K.Brahmachari, Latha P. Kadalayil, Majumdar, K. and Parnaik, V.K.
Proceedings of INDO-FRG seminar, BARC, (1983) : 106
- Critical cation balance in B«Z transition; Role of Li+.
Ramesh N. and Samir K. Brahmachari.
FEBS lett. (1983) 164: 33
- Temperature dependent ZÞB transitions in Poly (dG-dC).
Latha P. Kadalayil, Majumdar, K. and Samir K. Brahmachari.
Curr. Sci, (1983) 52: 907
- X-ray diffraction studies on Mycobacterium Smegmatis DNA.
Rajagopalan, M., Samir K. Brahmachari, V. Sasisekharan and Srivastava R.
Biopolymers (1983) 22(7): 1633
- Structural organization of the meotic prophase chromatin in the rat testis.
Rao B.J., Samir K. Brahmachari and Rao M.R.S.
J.Biol.chem, (1983) 258:13478
- A novel structural transition in poly (dG-Me5dC) :Z«B«Z.
Latha P.Kadalayil and Samir K. Brahmachari.
FEBS lett. (1985) 182:315
- Left handed DNA in synthetic and topologically constrained form V DNA and its implications in protein recognition.
Shouche,Y.S., Latha P.Kadalayil, Ramesh N., Majumder K., Mandyan V.
and Samir K. Brahmachari.
Proc. Int symp. Biomol. Struct Interactions,Suppl.J.Biosciences (1985) 8: 563
- Poly (dG-dC) in the Z-form inhibits E.Coli DNA polymerase I and AMV DNA polymerase activity.
Samir K. Brahmachari, Ramesh N., M.R.Das and Veena K.Parnaik.
Biochemistry Int. (1985) 11: 281
- B to Z transitions in DNA and their biological implications.
Latha P.Kadalayil and Samir K. Brahmachari.
J.Scientific & Industrial Res. (1986) 45: 521
- Sequence dependence and role of 5'-phosphate in B to Z transition.
Majumder K., Samir K. Brahmachari and V.Sasisekharan.
FEBS lett. (1986) 198: 240
- Use of volatile buffer at ambient temperature:Versatile approach to the purification of self complementary synthetic deoxyribonucleotides by reverse phase high performance liquid chromatography.
Majumder K.,Latha P.Kadalayil and Samir K.Brahmachari.
J.Chromatography (1986) 355: 328.
- Recognition of B and Z forms of DNA by E.Coli DNA polymerase.
Ramesh N.,Shouche Y.S. and Samir K. Brahmachari.
J.Mol.Biol. (1986) 190: 635
- DNA structural variability as a factor in gene expression and evolution.
Conrad M.,Samir K. Brahmachari and V. Sasisekharan.
Biosystems (1986) 19: 123
- Sequences that adopt non B-form conformation in form V DNA as probed by enzymatic methylation.
Samir K. Brahmachari, Shouche Y.S., Charles R. Cantor and M.McClelland.
J.Mol.Biol. (1987) 193: 201
- Synthesis and purification of Oligodeoxyribonucleotides:A modified approach.
Kumud Majumder, Latha P.Kadalayil and Samir K. Brahmachari.
Curr. Sci. (1987) 56: 693
- Torsional stress, Unusual DNA structures; and Eukaryotic gene expression.
C. R. Cantor, S. Bandopadhaya, Samir K. Brahmachari, C.F. Hui, M.McClelland, R. Morse and C. L. Smith.
Unusual DNA structure”; Ed. R.D. Wells and S.C. Harvey. Springer-Verlag, New York, (1988).
- Sequence specificity of Z-DNA formation in Oligonucleotides.
Latha P.Kadalayil, Kumud Majumder, R. K. Mishra and Samir K. Brahmachari.
Biochemistry Int. (1988) 17: 121
- Interruption of (CG)n sequences by GG, TG nad CA need not prevent B to Z transition in solution
R.K.Mishra, Latha P. Kadalayil and Samir K. Brahmachari.
Nucleic Acids Res. (1988) 16: 4651
- Synthesis of novel polynucleotide: Potential R-L model.
R.K.Mishra and Samir K. Brahmachari.
Curr. Sci. (1988) 57: 574
- Dynamic nature of B to Z transition: Role of DNA supercoiling and Z-DNA binding protein.
N. Ramesh and Samir K. Brahmachari.
Ind. J. Biochem. Biophys. Silver Jubilee issue (1988) 25: 542
- Sequence criteria for Z-DNA formation: Studies on poly d(ACGT).
Kumud Majumder, Rakesh K. Mishra, Manju Bansal and Samir K. Brahmachari.
Nucleic Acids Res. (1989) 17: 450
- Sequence specificity in supermine induced structural changes in CG-oligomers.
Kumud Majumder and Samir K. Brahmachari.
Biochemistry In., (1989) 18: 455
- Structural alteration from non-B to B-form could reflect Dnase I hypersensitivity.
N.Ramesh and Samir K. Brahmachari.
J.Biomol.Struc. Dynamics (1989) 6: 899
- Zintrons in rat alpha-Lactalbumin gene.
G.Meera, N.Ramesh and Samir K. Brahmachari.
FEBS lett (1989) 251: 245
- Preparation of Megabase DNA from adult insects and mammalian spleen for pulse field gel electrophoresis.
Vani Brahmachari, R.Nagasuma and Samir K. Brahmachari.
J. Genetics (1989) 68: 185
- Unusual DNA structures:Sequence requirements and role in transcriptional control.
Samir K. Brahmachari, N. Ramesh,Yogesh S. Souche, Rakesh K. Mishra, Rajesh Bagga and G. Meera.
Structures & Methods, Vol 2, Eds.R.H.Sarma & M.H. Sarma. Adenine press (1990)
- DNA duplex with a potential to change handedness after every half a turn.
Samir K. Brahmachari, Rakesh K.Mishra, Rajesh Bagga and N.Ramesh
Nucleic Acids Res. (1989) 17: 7273
- Role of Environment in the Interaction of Nonintercalators with Z-DNA.
K.Ekambareswara Rao, N.Ramesh, D.Chaudhary, Samir K. Brahmachari and
V.Sasisekharan
Journal of Biomolecular Structure & Dynamics (1989) 7: 335
- Probing of unusual DNA structures in topologically constrained from V DNA:Use of restriction enzyme as a structural probe.
ShoucheY.S., N.Ramesh and Samir K. Brahmachari
Nucleic Acids Res. (1990) 18: 267
- Supercoil induced unusual DNA structures as transcriptional block.
Rajesh Bagga, N.Ramesh and Samir K. Brahmachari
Nucleic Acids Res. (1990) 18: 3363
- Z-DNA Binding Protein Mediated Stabilization of the Z-conformation.
Samir K. Brahmachari, Eugenia T.Paulus, N.Krishnamachary and N.Ramesh
In Protein Structure-Function (1990), Ed.Zaidi, Abbasi & Smith,TWEL Publishers,135
- A novel approach to design cis-acting DNA structural elements for regulation of gene expression in vivo.
P.S.Sarkar,R.Bagga,P.Balagurumoorthy and Samir K. Brahmachari
Curr. Sci. (1991) 60: 586
- Distribution of simple repetitive (TG/CA)n and (CT/AG)n sequences in human and rodent genome.
Jalaj Tripathi and Samir K. Brahmachari
Journal of Biomolecular Structure & Dynamics. (1991) 9:387
- Synthetic gene design to investigate the role of cis-acting DNA structural elements in regulation of gene expression in vivo.
Samir K. Brahmachari, P.S.Sarkar, P.Balagurumoorthy, P.Burma and R.Bagga
Nucleic Acids Res., Symp. Series (1991) 24: 163
- Hairpin and parallel quartet structures for telomeric sequences.
P.Balagurumoorthy, Samir K. Brahmachari, Debasis Mohanty, Manju Bansal and V.Sasisekharan
Nucleic Acids Res. (1992) 20: 4061
- Intramolecular triplex potential sequence within a gene down regulates its expression in vivo.
P.S.Sarkar and Samir K. Brahmachari
Nucleic Acids Res (1992) 20: 5713
- Genome Analysis I: A new approach for visualization of sequence organization in genomes.
P.K.Burma, Alok Raj, Jayant K.Deb and Samir K. Brahmachari
Journal of Biosciences (1992) 17: 395
- Polypurine-polypyrimidine sequences adopt unwound structure in pBR322 from V DNA as probed by single-hit analysis of HpaII sites.
R.Bagga and Samir K. Brahmachari
Journal of Biomolecular Structure & Dynamics (1993) 10: 879
- Chaos game representations of similarities and differences between genomic sequences.
S.Baranidharan, B.Sankaranarayanan and Samir K. Brahmachari
International Journal of Genome Research (1994) 1: 309
- Intramolecular DNA triple helix and regulation of gene expression.
Samir K. Brahmachari and P.S.Sarkar
Structural Biology: State of Art 1993, Vol 2, Eds. R.H.Sarma and M.H.Sarma, Adenine press (1994)
- CA/TG sequence at the 5' end of oligo a-tracts strongly modulates DNA curvature.
Akhilesh K.Nagaich, D.Bhattacharya, Samir K. Brahmachari and Manju Bansal
J.Biol.Chem (1994) 269: 7824
- Structure and Stability of Human Telomeric Sequence.
P.Balagurumoorthy and Samir K. Brahmachari
J.Biol.Chem (1994) 269: 21858
- Synthetic gene design for modulation of gene expression in vivo.
Samir K. Brahmachari, Partha S.Sarkar, P.K.Burma, U.S.Shaligram and S.S.Pataskar
Proc. of the Ranbaxy Sym. On Mol. Genetics and Gene therapy,(1995), 85-97
- Functional significance of simple repetitive sequences in the genome.
Samir K. Brahmachari, G.Meera,Partha S.Sarkar, P.Balagurumoorthy, J.Tripathi, S.Raghavan, U.S.Shaligram and S.S.Pataskar
Electrophoresis (1995) 16: 1705-1714
- Analysis of CAG/CTG triplet repeats in the human genome: Implication in transcription factor gene regulation.
Rachna Bhandari and Samir K. Brahmachari
J. Biosci. (1995) 20: 613
- Intra and interloop interactions in the folded G quartet structure of Oxytricha telomeric
sequence.
P.Balagurumoorthy and Samir K. Brahmachari
Ind.J.Biochem.Biophys. (1995) 32: 385
- Polypurine/polypyrimidine sequences as cis acting transcriptional regulators.
Samir K. Brahmachari, Partha S.Sarkar, Sowmya Raghavan, Malthy Narayan and Amit K.Maiti
Gene (1997) 190: 17
- Positional preferences of polupurine/polypyrimidine sequences in the genome of
S.cerevisiae:Implications for cis-regulation of gene expression.
Sowmya Raghavan, Pradeep K.Burma and Samir K. Brahmachari
Journal of Molecular Evolution (1997) 45: 485-498
- Human genome studies and intellectual property rights: Whither national interest?
T R Sivaramjani and Samir K. Brahmachari
Current Science (1997) 72: 708
- International Collaboration in genetic research.
S. Chatterjee, Samir K. Brahmachari, S Jain, P. Majumder and T Reich.
Nature Genetics (1997) 15: 124
- Variation at the MJD locus in the major psychoses.
Q.Saleem, M.Vijayakumar, M.Mulsuddi, N.Chowdhary, S.Jain and Samir K. Brahmachari
Am.J.Med.Genet. (1998) 81(5): 440-442
- Correlation of Clinical Profile of Mytonic dystrophy with CTG repeats in Mtotonin Protein kinase gene.
M.Gourie-Devi, J.Ray Chaydhari, Anisya Vasanth, Q.Saleem, Mousumi Mutsuddi, Meera Gopinath, P.S.Sarkar and Samir K. Brahmachari
Ind.J.Med.Res. (1998) 107: 187-196
- Investigating the role of Trinucleotide repeats in schizophrenia and bipolar disorder.
Quasar Saleem, Sanjeev Jain and Samir K. Brahmachari
In the Proceedings of 5th Annual Symp., Ranbaxy Science Foundation. On Molecular Intervention in Disease (1998), 85-89
- Peptide models for inherited neurodegenerative disorders: conformation and aggregation properties of long polyglutamine peptides with and without interruptions
Deepak Sharma, Sunita Sharma, Santosh Pasha and Samir K. Brahmachari
FEBS. Lett. (1999) 456(1):181-185.
- The multitude of ‘omics’ and ‘omes’: Evolution of scientific terms in molecular biology in the new millennium.
Srinivasn Ramachandran, Debasis Dash, Samir K. Brahmachari
Current Science, (1999) 77(7): 846-847
- Polypurine/polypyrimidine repeats in complete bacterial genomes: Preference for
polypurine repeats in protein-coding regions (1999).
Sowmya Raghawan, Ramesh Hariharan and Samir K. Brahmachari
Gene (2000) 242: 275-283
- Association analysis of CAG repeats at the KCNN3 locus in Indian patients with Bipolar disorder and Schizophrenia.
Quasar Saleem, V.S. Sreevidya, J. Sudhir, J. Vijaya Savithri, Y. Gowda, V. Benegal, Chandrika B. Rao, Partha P. Majumder, Anuranjan Anand, Samir K. Brahmachari and Sanjeev Jain
Am.J.Med.Genet. (2000) 96, 744-748.
- Molecular analysis of autosomal dominant hereditary ataxias in the Indian population: High frequency of SCA2 and evidence for a common founder mutation.
Quasar Saleem, Shweta Choudhry, Mitali Mukherji, Leena Bashyam, M.V.Padma, Amber Chakravarthy, M.C.Maheshwari, Satish Jain and Samir K. Brahmachari
Human Genetics (2000) 106: 179-187.
- Association analysis of 5HT transporter gene in bipolar disorder in the Indian population.
Q. Saleem, S. Ganesh, M. Vijaykumar, Y.C.J.Reddy., Samir K. Brahmachari, Sanjeev Jain
Am. J. Med. Genet. (2000) 92(2): 170-172
- Probing the polyglutamine puzzle in neurological disorders.
Samir K. Brahmachari , Deepak Sharma , Sharma S, Santosh Pasha, Sen S, Quasar Saleem Q
FEBS Lett. (2000) 472(1): 167-168
- Association of CAG repeat Loci on Chromosome 22 with Schizophrenia and Bipolar Disorder.
Quasar saleem, Debasis Dash, Charu Gandhi, Anupam Kishore, Vivek Benegal, Tessi Sherrin, Odity Mukerjee, Sanjeev Jain and Samir K. Brahmachari
Mol. Psychiatry (2001) 6(6): 694-700
- Progressive Myoclonus Epilepsy [EPM1] repeat d(CCCCGCCCCGCG)n forms folded hairpin structures.
Shashank S. Pataskar, Debasis Dash and Samir K. Brahmachari
J. Biomol. Struct. Dynamics (2001) 19(2):293-305.
- Intramolecular I-motif structure at acidic pH for progressive Myoclonus Epilepsy [EPM 1] repeat d (CCCCGCCCCGCG)n.
Shashank S. Pataskar, Debasis dash and Samir K. Brahmachari
J. Biomol. Struct. Dynamics (2001) 19(2):307-313
- The polyglutamine motif is highly conserved at the clock locus in various organisms and is not polymorphic in humans.
Quasar Saleem, Anuranjan Anand, Sanjeev Jain and Samir K. Brahmachari
Human Genetics (2001) 109(2): 136-142
- CAG repeat instability at SCA2 Locus: anchoring CAA interuptions and linked single nucleotide polymorphism.
S. Choudhry, M. Mukerji, A. K. Srivastava, S. Jain, S. K. Brahmachari
Hum. Mol. Genet. (2001) 10(21):2437-2446
- Molecular and Clinical Correlation in five Indian families with Spinocerelellar Ataxia 12.
Achal K. Srivastava, Shweta Choudhry, Musuwadi S. Gopinath, Sanghamitra Roy, Manjari Tripathi, Samir K. Brahmachari, and Satish Jain
Annals of Neurology (2001) 50 (6) : 786-800
- Poly purine.pyrimidine sequences upstream of the beta-galactosidase gene affect gene
expression in Saccharomyces cerevisiae.
Maiti AK, Brahmachari SK
BMC Mol Biol (2001) 2(1):11
- A clinical study of patients with genetically confirmed Huntington's disease from India.
Murgod UA, Saleem Q, Anand A, Brahmachari SK, Jain S, Muthane UB
& J Neurol Sci (2001) 15;190(1-2):73-8
- Study of the Single Nucleotide Polymorphism (SNP) at the palindromic sequence of
Hypersensitive Site (HS)4 of the human ß -globin Locus Control region (LCR) in Indian
Population.
Ritushree Kukreti, Chandrika B-Rao, Swapan Kr Das, Madhusnata De, Geeta Talukder, Flavian Vaz, I. C. Verma, Samir K. Brahmachari
Am. J. Hemat. (2001) 69:77-79
- ACE insertion allele in relation to high altitude adaptation.
M. A. Qadar Pasha, AP Khan, Ratan Kumar, SK Grover, T Norboo, KK Srivastava, W. Selvamurthy, SK Brahmachari
Annals of Human Genetics (2001): 65: 531-536
- Expanding colonies and expanding repeats.
Quasar Saleem, Uday Murgod, Uday Muthane, Anuranjan Anand, Inder C Verma,
Samir K. Brahmachari, Sanjeev Jain.
Lancet (2002) 9; 359(9309): 895-6.
- Functional Genomics & DNA chips.
Samir K. Brahmachari
Appl Biochem Biotech (2001) 96/1-3: 9-12
- Genome-wide expression profile of RNA polymerase II subunit mutant of yeast using microarray technology.
Beena Pillai, Samir K. Brahmachari and PP. Sadhale
Current Science, (2001) 81,5, 574-578
- Angiotensin converting enzyme I/D polymorphism in ethnically different populations of India.
M A. Qadar Pasha, AP Khan, Ratan Kumar, SK Grover, KK Srivastava, W. Selvamurthy, SK Brahmachari
J. Biosci. (2002) 27: 67-70
- Molecular analysis of Huntingtons disease and linked polymorphisms in the Indian population.
Q. Saleem, S.Roy, U.Murgood, R.Saxeena, I.C. Verma, A.Anand, U.Muthane, S.Jain, S.Jain, S.K.Brahmachari
Acta Neurol Scand. 2003 Oct; 108(4): 281-286.
- Whole Genome Expression Profiles of Yeast RNA Polymerase II Core Subunit, Rpb4, in Stress and Nonstress Conditions.
Pillai B, Verma J, Abraham A, Francis P, Kumar Y, Tatu U, Brahmachari SK, Sadhale PP
J. Biol Chem. (2003) 278(5): 3339-46.
- A novel complexity measure for comparative analysis of protein sequences from complete genomes.
Nandi T, Dash D, Ghai R, Rao CB, Kannan K, Brahmachari SK, Ramakrishnan C, Ramachandran
J. Biomol Struct Dyn. (2003) 20(5): 657-68.
- Role of histidine interruption in mitigating the pathological effects of long polyglutamine stretches in SCA1: A molecular approach. Sen S., Dash D., Pasha S., and Brahmachari SK
Protein Science (2003) 12(05): 953-962
- Non-random distribution of Alu elements in genes of various functional categories: insight from analysis of human chromosomes 21 and 22.
Deepak Grover, Partha P. Majumder , Chandrika B. Rao, Samir K. Brahmachari , Mitali Mukerji
Molecular Biology and Evolution 2003 Sep; 20(9): 1420-4. Epub 2003 Jun 27.
- (TG:CA)(n) Repeats in Human Housekeeping Genes.
Sharma VK, Rao CB, Sharma A, Brahmachari SK, Ramachandran S.
J Biomol Struct Dyn. 2003 Oct; 21(2):303-10.
- Arterial oxygen saturation under hypoxic environment of high altitude associates with routine physical activities of natives.
M. A. Qadar Pasha, K. S. Kocherlakota, A. P. Khan, T. Norboo, S. K. Grover, M. A. Baig, W. Selvamurthy and S. K. Brahmachari
Current Science 2003; 85(4):502-506
- Association of high-altitude systemic hypertension with the deletion allele-of the angiotensin- converting enzyme (ACE) gene.
Kumar R, Qadar Pasha MA, Khan AP, Gupta V, Grover SK, Norboo T, Srivastava KK, Selvamurthy W, Brahmachari SK
Int J Biometeorol 2003; 48(1):10-14
- Hairpin-duplex equilibrium reflected in the A-->B transition in an undecamer quasi-palindrome present in the locus control region of the human beta-globin gene cluster.
Kaushik M, Kukreti R, Grover D, Brahmachari SK, Kukreti S.
Nucleic Acids Res. 2003 Dec; 1; 31(23):6904-15
- Recognition and analysis of protein coding genes in severe acute respiratory syndrome associated coronavirus.
Sharma R, Maheshwari JK, Prakash T, Dash D, Brahmachari SK.
Bioinformatics. 2004 May; 20(7): 1074-80
- Alu repeat analysis in the complete human genome: trends and variations with respect to genomic composition.
Grover D, Mukerji M, Bhatnagar P, Kannan K, Brahmachari SK.
Bioinformatics. 2004 Apr; 20(6): 813-17
- A nonsense mutation in the synaptogyrin 1 gene in a family with schizophrenia.
Verma R, Chauhan C, Saleem Q, Gandhi C, Jain S, Brahmachari SK.
Biol Psychiatry. 2004 Jan 15; 55(2):196-9
- CoPS: Comprehensive Peptide Signature Database.
Tulika Prakash, Mamta Khandelwal, Dipayan Dasgupta, Debasis Dash*, Samir K. Brahmachari.
Bioinformatics. 2004 Nov 1; 20(16):2886-8
- Evolution and distribution of RNA polymerase II regulatory sites from RNA polymerase III dependent mobile Alu elements.
Ravi Shankar, Deepak Grover, Samir K. Brahmachari and Mitali Mukerji
BMC Evolutionary Biology 2004, 4(1):37 (4 Oct 2004).
- Clusters of proteins in archaeal and bacterial proteomes using compositional analysis.
Nandi T, Brahmachari SK, Kannan K, Ramachandran S.
In Silico Biol. 2004;4(4):573-91.
- Conformational Analysis of Invariant Peptide Sequences in Bacterial Genomes.
Tulika Prakash, C. Ramakrishnan, Debasis Dash and Samir K. Brahmachari*
J Mol Biol. 2005 Feb 4; 345(5):937-55.
- Identification of a novel 45 repeat unstable allele associated with a disease phenotype at the MJD1/SCA3 locus.
Padiath QS, Srivastava AK, Roy S, Jain S, Brahmachari SK.
Am. J Med Genet B Neuropsychiatr Genet. 2005 Feb5; 133(1):124-6
- Assessing natural variations in gene expression in humans by comparing with monozygotic twins using microarrays.
Sharma A, Sharma VK, Horn-Saban S, Lancet D, Ramachandran S, Brahmachari SK.
Physiol Genomics. 2005 Mar 21; 21(1):117-23.
- Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes.
Ganapathi M, Srivastava P, Das Sutar SK, Kumar K, Dasgupta D, Singh GP, Brahmachari V, Brahmachari SK.
BMC Bioinformatics. 2005 May 26; 6(1):126.
- Sharma VK, Brahmachari SK, Ramachandran S.
(TG/CA)n repeats in human gene families: abundance and selective patterns of distribution according to function and gene length.
BMC Genomics. 2005 Jun 3; 6(1):83.
- Genomics and Functional Genomics
Mitali Mukerji, Beena Pillai, Somdutta Sen and Samir K. Brahmachari.
Textbook of Biotechnology, 2005, pp 1349-1409, Eds. Dr. H.K.Das, Wiley Dreamtech Pvt. Ltd, Delhi.
- Ritushree Kukreti, Pallav Bhatnagar, Chandrika B-Rao, Simone Gupta, Babita Madan, Chinmoyee Das, Randeep Guleria, Amita Umesh Athavale, Samir Kumar Brahmachari & Balaram Ghosh.
2-adrenergic receptor polymorphisms and response to salbutamol among Indian asthmatics.
Pharmacogenomics. Jun 2005; 6(4): 399-410.
- R. Verma, M. Mukerji, D. Grover, C. B-Rao, S. Das, S. Kubendran, S. Jain, S.K. Brahmachari.
MLC1 Gene Is Associated with Schizophrenia and Bipolar Disorder in Southern India.
Biological Psychiatry. 2005; 58(1):16-22.
- Grover D , Kannan K , Brahmachari SK , Mukerji M .
ALU-ring elements in the primate genomes.
Genetica. 2005 Jul;124(2-3):273-89.
- Manoj Hariharan, Vinod Scaria, Beena Pillai, Samir K. Brahmachari.
Targets for human encoded microRNAs in HIV genes.
Biochem Biophys Res Commun. 2005 Oct 7;337(4):1214-1218.
- The Indian Genome Variation Consortium (158 authors).
S.K. Brahmachari et.al.
The Indian Genome Variation database (IGVdb): a project overview.
Hum Genet. 2005; 118: 1–11.
- Verma R, Kubendran S, Das SK, Jain S, Brahmachari SK .
SYNGR1 is associated with schizophrenia and bipolar disorder in southern India.
J Hum Genet. 2005;50(12):635-40.
- Ritushree Kukreti, Sudipta Tripathi, Pallav Bhatnagar, Simone Gupta, Chitra Chauhan, Shobhana Kubendran, Y.C. Janardhan Reddy, Sanjeev Jain, Samir K. Brahmachari.
Association of DRD2 gene variant with schizophrenia.
Neurosci Lett. 2006 Jan 9;392(1-2):68-71.
- Simone Gupta, Sanjeev Jain, Samir K Brahmachari & Ritushree Kukreti.
Pharmacogenomics: a path to predictive medicine for schizophrenia.
Pharmacogenomics. 2006 Jan;7(1):31-47.
- Guzman MR , Liquier J , Brahmachari SK , Taillandier E .
Characterization of parallel and antiparallel G-tetraplex structures by vibrational spectroscopy.
Spectrochim Acta A Mol Biomol Spectrosc. 2006 May 15;64(2):495-503.
- Mukherjee O, Meera P, Ghosh S, Kubendran S, Kiran K, Manjunath KR, Subhash MN, Benegal V, Brahmachari SK, Majumder PP, Jain S.
Evidence of linkage and association on 18p11.2 for psychosis.
Am J Med Genet B Neuropsychiatr Genet. 2006 Aug 29; [Epub ahead of print]
- Simone Gupta; Siddharth S Bisht; Ritushree Kukreti; Sanjeev Jain; Samir K. Brahmachari.
Boolean Network Analysis of a Neurotransmitter Signaling Pathway.
J Theor Biol. 2007 Feb 7;244(3):463-9. Epub 2006 Aug 26.
- Scaria V, Hariharan M, Maiti S, Pillai B, Brahmachari SK.
Host-virus interaction : a new role for microRNAs.
Retrovirology. 2006 Oct 11;3(1):68.
- Sharma VK,Sharma A, Kumar N, Khandelwal M, Kumar Mandapati K, Horn-Saban S, Strichman- Almashanu L, Lancet D, Brahmachari SK, Ramachandran S.
Expoldb: expression linked polymorphism database with inbuilt tools for analysis of expression and simple repeats.
BMC Genomics. 2006 Oct 13;7:258.
- Ganapathi M, Singh GP, Sandhu KS, Brahmachari SK, Brahmachari V.
A whole genome analysis of 5' regulatory regions of human genes for putative cis-acting modulators of nucleosome positioning.
Gene. 2007 Apr 15;391(1-2):242-51. Epub 2007 Jan 26.
- Appelbe W, Auerbach AD, Becker K, Bodmer W, Boone DJ, Boulyjenkov V, Brahmachari S, Brody L, Brookes A, Brown AF, Byers P, Cantu JM, Cassiman JJ, Claustres M, Concannon P, Cotton RG, den Dunnen JT, Flicek P, Gibbs R, Hall J, Hasler J, Katz M, Kwok PY, Laradi S, Lindblom A, Maglott D, Marsh S, Masimirembwa CM, Minoshima S, de Ramirez AM, Pagon R, Ramesar R, Ravine D, Richards S, Rimoin D, Ring HZ, Scriver CR, Sherry S, Shimizu N, Stein L, Tadmouri GO, Taylor G, Watson M.
Recommendations of the 2006 Human Variome Project meeting
Nature Genetics. 2007 Apr; 39(4):433-6.
- Scaria V, Hariharan M, Brahmachari SK, Maiti S, Pillai B.
microRNA: an Emerging Therapeutic
ChemMedChem. 2007 Apr 5;2(6):789-792.
- Sharma VK, Kumar N, Brahmachari SK, Ramachandran S.
Abundance of Dinucleotide Repeats and Gene Expression are Inversely Correlated: a role for gene function in addition to intron length.
Physiol Genomics. 2007 Sep 19;31(1):96-103.
- Prakash T, Sandhu KS, Singh NK, Bhasin Y, Ramakrishnan C, Brahmachari SK.
Structural assessment of glycyl mutationsin invariantly conserved motifs.
Proteins. 2007 Jul 10; 69(3):617-632.
- Kumar HB, Purushottam M, Kubendran S, Gayathri P, Mukherjee O, Murthy AR, Ghosh S, Chandra P, Reddy YC, Benegal V, Brahmachari SK, Jain S.
Serotonergic candidate genes and puerperal psychosis: an association study.
Psychiatr Genet. 2007 Oct;17(5):253-260.
- Ghosh T, Pandey N, Maitra A, Brahmachari SK, Pillai B.
A role for voltage-dependent anion channel Vdac1 in polyglutamine-mediated neuronal cell death.
PLoS ONE. 2007 Nov 14;2(11):e1170.
- Vinod Scaria, Manoj Hariharan, Beena Pillai, Souvik Maiti and Samir K. Brahmachari.
Host–virus genome interactions: macro roles for microRNAs.
Cell Microbiol. 2007 Dec;9(12):2784-94. Epub 2007 Oct 18. Review.
- Mathivanan S, Ahmed M, Ahn NG, Alexandre H, Amanchy R, Andrews PC, Bader JS, Balgley BM, Bantscheff M, Bennett KL, Björling E, Blagoev B, Bose R, Brahmachari SK, Burlingame AS, Bustelo XR, Cagney G, Cantin GT, Cardasis HL, Celis JE, Chaerkady R, Chu F, Cole PA, Costello CE, Cotter RJ, Crockett D, DeLany JP, De Marzo AM, DeSouza LV, Deutsch EW, Dransfield E, Drewes G, Droit A, Dunn MJ, Elenitoba-Johnson K, Ewing RM, Van Eyk J, Faca V, Falkner J, Fang X, Fenselau C, Figeys D, Gagné P, Gelfi C, Gevaert K, Gimble JM, Gnad F, Goel R, Gromov P, Hanash SM, Hancock WS, Harsha HC, Hart G, Hays F, He F, Hebbar P, Helsens K, Hermeking H, Hide W, Hjernø K, Hochstrasser DF, Hofmann O, Horn DM, Hruban RH, Ibarrola N, James P, Jensen ON, Jensen PH, Jung P, Kandasamy K, Kheterpal I, Kikuno RF, Korf U, Körner R, Kuster B, Kwon MS, Lee HJ, Lee YJ, Lefevre M, Lehvaslaiho M, Lescuyer P, Levander F, Lim MS, Löbke C, Loo JA, Mann M, Martens L, Martinez-Heredia J, McComb M, McRedmond J, Mehrle A, Menon R, Miller CA, Mischak H, Mohan SS, Mohmood R, Molina H, Moran MF, Morgan JD, Moritz R, Morzel M, Muddiman DC, Nalli A, Navarro JD, Neubert TA, Ohara O, Oliva R, Omenn GS, Oyama M, Paik YK, Pennington K, Pepperkok R, Periaswamy B, Petricoin EF, Poirier GG, Prasad TS, Purvine SO, Rahiman BA, Ramachandran P, Ramachandra YL, Rice RH, Rick J, Ronnholm RH, Salonen J, Sanchez JC, Sayd T, Seshi B, Shankari K, Sheng SJ, Shetty V, Shivakumar K, Simpson RJ, Sirdeshmukh R, Siu KW, Smith JC, Smith RD, States DJ, Sugano S, Sullivan M, Superti-Furga G, Takatalo M, Thongboonkerd V, Trinidad JC, Uhlen M, Vandekerckhove J, Vasilescu J, Veenstra TD, Vidal-Taboada JM, Vihinen M, Wait R, Wang X, Wiemann S, Wu B, Xu T, Yates JR, Zhong J, Zhou M, Zhu Y, Zurbig P, Pandey A.
Human Proteinpedia enables sharing of human protein data.
Nat Biotechnol. 2008 Feb;26(2):164-7. No abstract available.
- Elayanambi Sundaramoorthy, Souvik Maiti, Samir K. Brahmachari, Shantanu Sengupta.
Predicting protein homocysteinylation targets based on dihedral strain energy and pKa of cysteines.
Proteins. 2008 May 15;71(3):1475-83.
- The Indian Genome Variation Consortium (150 authors).
S.K. Brahmachari et.al.
Genetic Landscape of the People of India: a Canvas for Disease Gene Exploration.
Journal of Genetics, Vol. 87, No. 1, April 2008
- Prasher B, Negi S, Aggarwal S, Mandal AK, Sethi TP, Deshmukh SR, Purohit SG, Sengupta S, Khanna S, Mohammad F, Garg G, Brahmachari SK; Indian Genome Variation Consortium, Mukerji M.
Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda
J Transl Med. 2008 Sep 9;6:48.
- Hardy BJ, Séguin B, Singer PA, Mukerji M, Brahmachari SK, Daar AS
From diversity to delivery: the case of the Indian Genome Variation initiative.
Nat Rev Genet. 2008 Oct;9 Suppl 1:S9-14.
- Thorisson GA, Lancaster O, Free RC, Hastings RK, Sarmah P, Dash D, Brahmachari SK, Brookes AJ.
HGVbaseG2P: a central genetic association database.
Nucleic Acids Res. 2009 Jan;37 (Database issue):D797-802. Epub 2008 Oct 23
- Ahluwalia JK, Khan SZ, Soni K, Rawat P, Gupta A, Hariharan M, Scaria V, Lalwani M, Pillai B, Mitra D, Brahmachari SK.
Human cellular microRNA hsa-miR-29a interferes with viral nef protein expression and HIV-1 replication
Retrovirology. 2008 Dec 23;5(1):117.
- Taneja B, Yadav J, Chakraborty TK, Brahmachari SK.
An Indian effort towards affordable drugs: "generic to designer drugs".
Biotechnol J. 2009 Mar 18;4(3):348-60
- Gupta M, Bhatnagar P, Grover S, Kaur H, Baghel R, Bhasin Y, Chauhan C, Verma B,
Manduva V, Mukherjee O, Purushottam M, Sharma A, Jain S, Brahmachari SK, Kukreti R.Association studies of catechol-O-methyltransferase (COMT) gene with schizophrenia and response to antipsychotic treatment.
Pharmacogenomics. 2009 Mar;10(3):385-97.
- Sharma A, Kumar M, Aich J, Hariharan M, Brahmachari SK, Agrawal A, Ghosh B.
Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a.
Proc Natl Acad Sci U S A. 2009 Mar 23. [Epub ahead of print]
PMID: 19307576
Papers Published by Dr. Brahmachari’s Students, Associates and Group:
(Where SKB is not an author)
- A new polymer supported packing material as a substitute of Hydroxylapatite:Purification of Topoisomerases.
K.Majumder and N.Ramesh.
Chromatographia (1987) 24: 400
- Preparation and characterisation of a new Matrix: Polymer supported Hydroxlapatite Substitute. Majumder, K.
Biol.Chem. Hoppe-Seyler (1987) 368: 760
- Screening of clones containing altered DNA conformations by plasmid topoprofile shift.
N.Ramesh and R.K.Mishra.
J.Biochem.Biophys.Meth. (1991) 22: 171
- Hereditary ataxia with ophthalmoplegia-preliminary observations on a Bengali family with autosomal dominant inheritance.
Ambar Chakravarty, Angshuman Mukerjee, Somaditya Banerjee and Quasar Saleem.
J. of Association of Neuroscientists of Eastern India (1996) 1: 188
- Molecular Analysis of Friedreich’s Ataxia locus in the Indian Population.
M.Mukerji, S. Choudhry, Q.Saleem, M.V.Padma, M.C. Maheshwari, S. Jain
Acta Neurologica Scandinavica (2000) 102(4): 227-229
- Sample Size considerations in genetic polymorphism studies.
Chandrika B. Rao.
Human Heredity (2001) 52(4): 191-200
- “Spectrum of b-thalassaemia mutations and their association with allelic sequence polymorphisms at the b-globin gene cluster in eastern Indian population”.
Ritushree Kukreti, Debasis Dash, Vineetha K E, Sanchita Chakravarty, Swapan Kr Das, Madhusnata De, Geeta Talukder.
American Journal of Hematology (2002) 70(4):269-77.
- Origin and instability of GAA repeats: insights from Alu elements.
Chauhan C, Dash D, Grover D, Rajamani J, Mukerji M.
J Biomol Struct Dyn. 2002 Oct; 20(2):253-63.
- Spectrum of beta-thalassemia mutations and their association with allelic sequence polymorphisms at the beta-globin gene cluster in an Eastern Indian population.
Kukreti R, Dash D, E VK, Chakravarty S, Das SK, De M, Talukder G
Am J Hematol. 2002 Aug; 70(4):269-77.
- In silico characterization of the INO80 subfamily of SWI2/SNF2 chromatin remodeling proteins. Bakshi R, Prakash T, Dash D, Brahmachari V.
Biochem Biophys Res Commun. 2004 Jul 16; 320(1):197-2.
- Comparative analysis of protein unfoldedness in human housekeeping and non-housekeeping proteins.
Pandey N, Ganapathi M, Kumar K, Dasgupta D, Sutar SD, Dash D.
Bioinformatics. 2004 Nov 22; 20(17):2904-10
- SMARCA2 and THAP11: potential candidates for polyglutamine disorders as evidenced from polymorphism and protein-folding simulation studies.
Pandey N, Mittal U, Srivastava AK, Mukerji M.
J Hum Genet. 2004; 49(11):596-602. Epub 2004 Sep 10.
- ArrayD: a general purpose software for microarray design.
Sharma A, Srivastava GP, Sharma VK, Ramachandran S.
BMC Bioinformatics. 2004 Oct 2;5:142.
- Founder Haplotype for Machado-Joseph Disease in the Indian Population: Novel Insights from History and Polymorphism Studies.
Uma Mittal; Achal K. Srivastava; Satish Jain; Sanjeev Jain; Mitali Mukerji.
Arch Neurol 2005; 62 637-640.
- Post-zygotic de novo trinucleotide repeat expansion at spinocerebellar ataxia type 7 locus: evidence from an Indian family.
Mittal U, Roy S, Jain S, Srivastava AK, Mukerji M.
J Hum Genet. 2005; 50(3):155-7. Epub 2005 Mar 5.
- Evidence of a Common Founder for SCA12 in the Indian Population. S. Bahl K. Virdi, U. Mittal, M. P. Sachdeva, A. K. Kalla, S. E. Holmes, E. O'Hearn, R. L. Margolis, S. Jain, A. K. Srivastava and M. Mukerji.
Ann Hum Genet. 2005 Sep; 69(Pt 5):528-34.
- Insights into the mutational history and prevalence of SCA1 in the Indian population through anchored polymorphisms.
Mittal U, Sharma S, Chopra R, Dheeraj K, Pal PK, Srivastava AK, Mukerji M.
Hum Genet.
2005 Nov; 118(1):107-14. Epub. 2005 Oct 28.
- SPAAN: a software program for prediction of adhesins and adhesin-like proteins using neural networks.
Sachdeva G, Kumar K, Jain P, Ramachandran S.
Bioinformatics. 2005 Feb 15;21(4):483-91. Epub 2004 Sep 16.
- Intrinsic unstructuredness and abundance of PEST motifs in eukaryotic proteomes.
Singh GP, Ganapathi M, Sandhu KS, Dash D.
Proteins. 2006 Feb 1; 62(2):309-15.
- Simple sequence proteins in prokaryotic proteomes.Subramanyam MB, Gnanamani M, Ramachandran S.
BMC Genomics. 2006 Jun 8;7:141.
- Conformational flexibility may explain multiple cellular roles of PEST motifs.
Sandhu KS, Dash D.
Proteins. 2006 Jun 1; 63(4):727-32.
- DyNAVacS: an integrative tool for optimized DNA vaccine design.
Harish N, Gupta R, Agarwal P, Scaria V, Pillai B.
Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W264-6.
- Quadfinder: server for identification and analysis of quadruplex-forming motifs in nucleotide sequences.Scaria V, Hariharan M, Arora A, Maiti S.
Nucleic Acids Res. 2006 Jul 1;34(Web Server issue):W683-5.
- Bhatnagar P, Guleria R, Kukreti R.
Pharmacogenomics of beta2-agonist: key focus on signaling pathways.
Pharmacogenomics. 2006 Sep;7(6):919-33. Review.
- Ravi Shankar, Amit Chaurasia, Biswaroop Ghosh, Dmitry Chekmenev, Evgeny Cheremushkin, Alexander Kel, Mitali Mukerji.
Non-random genomic divergence in repetitive sequences of human and chimpanzee in genes of diVerent functional categories.
Mol Genet Genomics (2007) 277:441–455.
- Singh GP, Ganapathi M, Dash D.
Role of intrinsic disorder in transient interactions of hub proteins.
Proteins. 2007 Mar 1;66(4):761-5.
- Sandhu KS, Dash D.
Dynamic alpha-helices: conformations that do not conform.
Proteins. 2007 Jul 1;68(1):109-22.
- Singh GP, Dash D.
Intrinsic disorder in yeast transcriptional regulatory network.
Proteins. 2007 Aug 15;68(3):602-5.
S. No. |
Title |
Inventors |
Country
(Publicatoin Date) |
Filing Date |
Grant Date |
Patent No. |
1.
|
Computational method for identifying adhesin and adhesin- like proteins of therapeutic potential |
Sachdeva Gaurav, Kumar Kaushal, Preti Jain, Brahmachari SK, Ramachandran S |
India |
29-May-06 |
|
|
US |
20-Jul-04 |
|
|
WO |
07-Feb-05 |
|
|
2.
|
A computer based method for identifying conserved invariant peptide motifs |
Brahmachari SK, Dash D |
BR
(14-Jan-03) |
30-Sep-02 |
|
|
CA
(11-Oct-01) |
07-Dec-01 |
|
|
CN |
26-Nov-02 |
20-Jul-05 |
218305 |
CZ
(15-May-02) |
04-Jan-02 |
|
|
EP
(02-Jan-03) |
31-Aug-00 |
12-Jan-05 |
1268512 |
EP |
26-Feb-02 |
|
|
HU
(28-May-03) |
30-Sep-02 |
|
|
India |
16-Sep-02 |
|
|
IS |
01-Jan-02 |
|
|
JP
(30-Sep-03) |
24-Jan-02 |
|
|
KO |
14-Jan-02 |
|
|
RU |
12-Jan-02 |
27-Mar-05 |
2249044 |
US |
30-Mar-00 |
|
|
WO
(17-Feb-05) |
31-Aug-00 |
|
|
3.
|
A method for predicting an individual's bronchodilatory response to a beta agonist |
Somesh Sharma, Kukreti R, Pallav Bhatnagar, Rao CB, Ghosh B, Brahmachari SK, Randeep Guleria |
India |
10-Dec-04 |
|
|
US |
28-Apr-04 |
|
|
WO |
29-Apr-04 |
|
|
4.
|
Targets for human micrornas in avian influenza virus (H5N1) genome |
Samir Kumar Brahmachari, Manoj Hariharan, Vinod Scaria, Beena Pillai |
India |
31-Mar-06 |
|
|
5.
|
A novel computer based method for identification of candidate proteins useful as anti-infectives |
Brahmachari SK, Ramachandran S, Rao CB |
US |
30-Mar-01 |
|
|
6.
|
Novel allelic variant of cyp2c19 associated with drug metabolism |
Brahmachari SK, Ravina Fernandes, Sharma Nitin, Suparna Martis, Kukreti R, Mukerji M, |
India |
15-Jul-04 |
|
|
US |
15-Jul-05 |
|
|
WO |
15-Jul-05 |
|
|
7.
|
Method of detection of allelic variants of SCA2 gene |
Brahmachari SK, Choudhry Shweta, Mukerji Mitali, Jain Satish |
US
(23-Sep-03) |
08-Nov-00 |
23-Sep-03 |
6623927 |
8.
|
Targets for human micrornas in HIV-1 genome and a method thereof. |
Brahmachari SK, Pillai B, Manoj Hariharan |
India |
10-Oct-05 |
|
|
9.
|
Novel primers for screening schizophrenia and a method thereof |
Brahmachari SK, Ranjana, Chitra, Salim Q, Jain S |
AU |
27-Mar-03 |
|
|
BR |
31-Mar-03 |
|
|
CA |
27-Mar-03 |
|
|
EP |
31-Mar-03 |
|
|
IL |
27-Mar-03 |
|
|
India |
06-Aug-04 |
|
|
JP |
28-Mar-03 |
|
|
US |
21-Mar-02 |
20-Jul-04 |
6764824 |
WO |
25-Mar-02 |
|
|
10.
|
A computer based method for predicting protein coding dna sequences useful as drug targets |
Brahmachari SK, Dash D, Ramakant Sharma, Jitendra Kumar Maheshwari |
India |
30-Jun-05 |
|
|
US
(23-Jun-05) |
05-Dec-03 |
|
|