1. New targets and markers for cancer using genomics and proteomics

2. Stimuli sensitive polymeric nano-particle based advanced drug delivery systems for cancer, diabetes and anti-bacterials

3. Latent M. Tuberculosis: New Targets, Drug Delivery system, bio-enhancers and therapeutics & Clinical Trials

4. Herbal based preparations for degenerative disorders: Diabetes mellitus type II (NIDDM) with emphasis on insulin sensitization and Herbopoint & Herbal based preparations for degenerative disorders: Osteoarthritis and rheumatoid arthritis especially for pain management & Herbal based preparations for degenerative disorders: Common hepatic disorders with emphasis on hepatocellular protection and herboprint

5. Development of an Oral herbal formulation for treatment of Psoriasis a clinical and scientific challenge

6. Development of novel biotech therapeutic molecule –Lysostaphin & Novel Biotherapeutic Molecule: Lysostaphin – Phase IIb/III Clinical studies

7. Microbiological conversion of Erythromycin to Clarithromycin and other novel biologically active molecules

8. Novel Molecular Diagnostics for Eye Diseases and Low Vision Enhancement Devices

& Development of DNA Macroarray for the detection of eye infections and the genetic predisposition to glaucoma

9. Oral Delivery of Insulin

10. Process for Tamiflu – a Blockbuster drug to combat the menace of avian flu

11. A prospective study to correlate gene signatures with clinical outcome of astrocytomas and identification of potential therapeutic target(s).

12. Development of an integrated micro PCR system with In-situ Identification - Phase II

13. Novel method for development of B-type Natriuretic peptide (BNP) for diagnosis and treatment of congestive heart failure

14. Novel formulation for treatment of pulmonary tuberculosis – clinical studies

15. Novel therapy for management of sepsis

16. A syndromic approach to diagnosis of infections: development of DNA macro-chips for simultaneous detection of pathogens causing AES (Acute Encephalitic Syndrome) and septicemia

17. Development and characterization of an indigenous vaccine for Johne’s disease

18. Development of Caerulomycins as novel immunosuppressive agents to prevent organ rejection after transplantation and to address various auto-immune and allergic disorders

19. Novel DPP IV inhibitors for the treatment of Diabetes & Novel DPP IV inhibitor – Phase I/II Study: A safety, pharmacokinetic and pharmacodynamics study of CPL-2009-0031 in Healthy Volunteers and patients with Type 2 Diabetes mellitus

20. Development and production of a therapeutic monoclonal antibody against eNAMPT, a novel inflammatory target

21. Discovery and Validation of New Biomarkers for Head & Neck Cancer in India

22. Customized adaptation of non ClonableID technology to establish authenticity of medical products

23. Development of a diagnostic system for affordable, point of need testing to manage HIV and TB

24. Development of an antidiabetic agent based on the Phytopharmaceutical drug guidelines from Enicostemma littorale blume.

25. Development of selected Medical Implants

& Development of Dental Implants-Phase II study

1. Using Functional genomics in tea, Mentha, Ashwagandha, plants for gene expression modulation

2. Biodegradable plastics from agricultural wastes: Cellulose esters based on bagasse

3. Pharmacological and Genomic Investigations on Withania somnifera - An Indian Medicinal Plant & Leads based drug development and genetic improvement of Ashwagandha (Withania somnifera)

4. Novel expression system

5. Development of Novel Fungicides

6. Biotechnological Approaches for Improvement of Plant Species with Special Reference to Pulp and Paper

7. Genetic Improvement of Jatropha curcas for Adaptability and Oil Yield

8. Development of production system for Tea Polyphenols and their condensed products

9. Development of high throughput marker assisted selection systems for improvement of drought tolerance and fibre quality related traits in cotton

10. Novel approaches for production of hybrid seeds with characteristics of improved insect resistance and higher yield

11. Evaluation of RNAi-based constructs for conferring resistance on transgenic rice against the blast fungus Magnaporthe grisea

12. Kappaphycus alvarezii and Red seaweed based formulations for improving productivity and health of dairy and poultry animals.

1. Meso-scale modeling for monsoon predictions and Mesoscale modeling for Monsoon Predictions-Phase II

2. Environmentally secure rare earth based colorants for surface coatings

3. Nano-Material Coatings and Advanced Composites for Tribological Applications in Automotive Industry

4. Development of Next Generation Plasma Display Technology and a 50-Inch-High Definition (HD) TV prototype

5. Design and development of cushion bonded organic ceramic clutch discs

6. Development and commercialization of NXR-4D: A lithium-Ion battery powered 4-door next generation electric Car (4-Seater Capacity) -

7. Design and fabrication of All-Fiber Supercontinuum Light Source with application demonstration on spectroscopic signature detection

8. Development and commercialization of Soleckshaw Lite – An Innovative Electrical Green Transport Platform:

9. Development of integrated technological solutions for security and operations based on UV sensor technologies

10. Design and development of photonic crystal cladded and double called Er and Er/Yb fibers, and application demonstration of high-power optical amplifier

11. Automation of Ghani operation through vacuum conveying system

1. 5 & 25 KW decentralized power packs

2. Improved granular processing: towards energy efficiency and resource conservation in cement manufacture

3. Functionalization of alkanes

4. Development of fuel cells based on Hydrogen; Development and demonstration of polymer electrolyte fuel cell stacks for stationary applications; & Demonstration and Validation of 3kWe PEMFC System

5. Development of a 500 kW low cost horizontal-axis Wind Turbine

6. Biofuel from Marine Microalgae

7. Design, Dev. and demonstration of high performance Parabolic Trough based 300 kW Solar Thermal Power Plant

8. Dev. and demonstration of 500W SOFC Stack with hydrogen as fuel and testing of short stack with synthetic gas

& Development and demonstration of 1 kWe SOFC Stack with hydrogen & Air and 500 We SOFC

9. The next generation wind power technology: contra-Rotor Wind Turbine (CRWT) System

10. Demonstration and validation of a 5KW HT-PEMFC based combined cooling and power system

11. Demonstration and validation of a LT-PEMFC system for Automotive application

12. Stack with reformed natural Gas and Air

1. Two orders of magnitude improved liquid crystals for flat panel display devices

2. Defunctionalization of carbohydrates as a feed stock to manufacture well identified industrial chemicals

3. Nano-material catalysts and associated process technology for alkylation/ acylation/nitration of well identified industrial chemicals, pre-reforming of hydro-carbons and sulphur removal (<50 ppm) from petroleum fuels

4. Biotechnology for replacing chemical process in leather sector- Phase I & Phase II

5. Value added polymeric materials from renewable resources: Lactic acid and lactic acid based polymer

& Lactic acid and lactic acid based polymers-establishment of 300 TPA pilot plant for lactic acid production

6. Recombinant approach to produce a-linolenic acid and docosahexanoic acid (DHA) in sunflower and yeast

7. Conversion of cellulose and hemi-cellulose into sugars and ethanol

8. Conversion of Bioglycerol into value added chemicals & Scale up of CSIR-NCL process for selective hydrogenolysis of glycerol to 1, 2- Propanediol- Phase 2

9. Development of non-hazardous process for the synthesis of Di Methyl Carbonate (DMC) from methanol and urea

1. Versatile, portable PC based software for bioinformatics and Development of Linux cluster version of Bio-suite

2. A cost effective Simple Office Computing (Sofcomp) platform to replace PC

3. Market seeding of SofComp and Mobilis to develop wide-ranging applications as well as increase awareness

4. A PC based high-end 3D visualization platform for computational biology – ‘Darshee’

5. Improved Genome Annotation Through A Combination Of Machine Learning And Experimental Methods: Plasmodium Falciparum As A Case Study

6. Development of Globally competitive ‘Triple-Play’ Broadband Technology

7. Wireless Sensor Network Chipset based on Ultra –Wideband Technology

8. Development of Intelligent video surveillance server system

9. Development and commercialization of “Vennfer” – unique H.264 high definition software based multiparty, multipoint video conferencing solution on multipoint network transmission protocol

10. System based computational model of skin (SCoMOS)